Libre Pathology - User contributions [en]

User talk:Maxwell

2025-07-13T11:02:41Z

Rudolf: Welcome!

Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
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*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 11:02, 13 July 2025 (UTC))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 11:02, 13 July 2025 (UTC)

LP:Sandbox

2022-02-06T04:29:38Z

Rudolf: Reverted edits by Talent (talk) to last revision by Michael

User talk:Talent

2020-11-07T14:14:14Z

Rudolf: Welcome

Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 09:14, 7 November 2020 (EST))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 09:14, 7 November 2020 (EST)

User talk:Ipshita

2018-10-04T14:12:38Z

Rudolf: welcome

Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 10:12, 4 October 2018 (EDT))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 10:12, 4 October 2018 (EDT)

User talk:Brigitte

2018-04-04T02:32:00Z

Rudolf: create

Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 22:31, 3 April 2018 (EDT))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 22:31, 3 April 2018 (EDT)

User talk:John

2017-05-23T04:17:27Z

Rudolf: thanks, welcome

==Case 52==
Hello John,

Thanks for the comments on the [[Talk:Case_52]] page!

I have changed the IHC findings based on your comments. In general, the IHC findings are approximate; they aren't exactly what was in the case... as I usually don't have that recorded. Broadly speaking the IHC findings are similar to what one would find in a textbook... which usually mirror what is seen in practice.

Once again thanks of the comments!
[[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 00:17, 23 May 2017 (EDT)

==A belated general welcome==
Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 00:17, 23 May 2017 (EDT))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 00:17, 23 May 2017 (EDT)

Case 52

2017-05-23T04:11:25Z

Rudolf: fixing IHC

===Provided clinical history===
36 year old man, hemoptysis

===Site===
Left [[lung]]

===Primary image===
[[Image: Lung carcinoid - low mag.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Lung carcinoid - high mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Lung carcinoid - very high mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[Pulmonary carcinoid tumourlet]], [[Atypical carcinoid lung tumour]], [[Typical carcinoid lung tumour]], [[Adenocarcinoma of the lung]] </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>No history of smoking. History of MEN sydrome.</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>This is a neuroendocrine tumor. </center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| ae1ae3= '''POSITIVE'''
| a1at=
| acth=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56= '''POSITIVE'''
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cd57/Leu7=
| cea=
| chromo= '''POSITIVE'''
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gcdfp=
| gfap=
| gh=
| glucagon=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67= <3% of tumour cells
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| melanin_a=
| mitf=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| s100=
| sma=
| somatsatin=
| synapto= '''POSITIVE'''
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1= '''POSITIVE'''
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Chromosomal translocations====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t2_13=
| t21_22=
| t8_14=
| t9_22=
| t9_22=
| tx_17=
| tx_18=
}}
===Diagnosis===
{{hidden|Diagnosis|<center>[[Typical carcinoid lung tumour]]</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]

[[Category:Cases in pulmonary pathology]]
[[Category:Cases difficulty 2]]
[[Category:Cases in pulmonary pathology - junior]]

Wikimedia Commons

2017-04-18T13:15:22Z

Rudolf: tweak

[[Image:Commons-logo-en.svg|thumb|right|The Wikimedia Commons logo.]]
'''Wikimedia Commons''', abbreviated as '''WC''' and also known as '''WikiCommons''' and '''Commons''', is the repository for images and multimedia files for the Wikimedia Foundation, the foundation behind [[Wikipedia]] and a number of other large projects.

===Relation ''Libre Pathology''===
There is no official affiliation; however, most media for this site originates from the WikiCommons and new media for this site is generally uploaded there, as this site supports the mission of the WikiMedia Foundation (WMF).

''[[Libre Pathology]]'' makes use of Wikimedia Commons media via the ''InstantCommons'' feature of [[Mediawiki]].<ref>URL: [http://www.mediawiki.org/wiki/InstantCommons http://www.mediawiki.org/wiki/InstantCommons]. Accessed on: 30 March 2014.</ref>

===Why contribute to the WikiCommons?===
The images are available to WMF projects. It is part of [[Libre Pathology]]'s commitment to open content.

==See also==
*[[Mediawiki]].
*[[Wikipedia]].
*[[Image annotation]].

==References==
{{Reflist|1}}

==External links==
*[http://commons.wikimedia.org/wiki/Main_Page Wikimedia Commons (WC)].
*[http://en.wikipedia.org/wiki/Wikimedia_Foundation Wikimedia Foundation (WP)].
*[http://en.wikipedia.org/wiki/Open_content Open content (WP)]

[[Category:Stuff]]

Libre Pathology:Welcome

2016-12-30T17:36:09Z

Rudolf: /* Welcome email */ update

This is the '''welcome''' page for new editors.
At this point it just has a welcome message that is useful for saying ''hello'' and giving a few pointers.

''LP:Weclome'' and ''LP:New'' redirect here.

==Welcome message==
<pre>
Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: <nowiki>~~~</nowiki>. Four tildes (<nowiki>~~~~</nowiki>)
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. ~~~~
</pre>

==Welcome email==
<pre>
Hello XXXX,

We are always happy to have help. I created an account for you
on Libre Pathology.

The user name is: XXXX

You should have an email with a temporary password in your mailbox.
Your email ( XXXX ) allows you to reset the password, should you
forget it. You can change the email address in the preferences --
if you want it to be something else
( https://librepathology.org/wiki/Special:Preferences ).
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Work on things you are interested in when you have time. Every
little bit is appreciated.

All edits can be undone. So, we encourage you to just try things.

If you want to read an introduction to editing--one can be found here:
https://librepathology.org/w/images/7/71/Intro_to_Editing_Libre_Pathology_2016_v4.pdf

If you have any questions don't hesitate to send me an email.

Welcome to Libre Pathology!
YYYY
</pre>

==See also==
*[[Libre Pathology]].

[[Category:Libre Pathology]]

Libre Pathology:Editing

2016-12-30T17:33:42Z

Rudolf: /* A general introduction to editing Libre Pathology */ fix

[[Image:Libre Pathology - logo - white background.png|250px|thumb|The Libre Pathology logo.]]
This article is about '''editing [[Libre Pathology]]'''. This site has a closed editorship but an open door policy. If you would like to contribute by editing, send a short email to: ''gettinginvolved@librepathology.org''.

If editing is not your thing but want to help, take a look at the ''[[Libre Pathology:Contributing|contributing]]'' article.

==A general introduction to editing Libre Pathology==
*A PDF that describes editing, in general terms, can be found [https://librepathology.org/w/images/7/71/Intro_to_Editing_Libre_Pathology_2016_v4.pdf here].

==General editing guidelines==
*Editors are required to disclose all pertinent commercial relationships.
*[[LP:No original research|We don't do original research]].
*[[Libre Pathology:Verifiability|Evidence... that's what we want]]!

==Introduction to the wiki mark-up==
{{Main|Help:How to edit}}
<pre>
'''bold'''

''italics''

==Heading==

===Subheading===

[[Image:name of image.jpg|thumb|A caption.]]

<ref>This is a reference.</ref>

{{Reflist}}
</pre>

==See also==
*[[Libre Pathology:Manual of style]].
*[[Libre Pathology:References]].

[[Category:Libre Pathology]]

LP:Sandbox

2016-10-28T21:11:35Z

Rudolf: /* Section */

MediaWiki:Sitenotice

2016-05-31T04:10:10Z

Rudolf: remove survey

Libre Pathology:Contact us

2016-05-04T05:05:55Z

Rudolf: /* See also */

The page is about how to '''contact us'''. If you have a general question, the answer may be in the ''[[Libre Pathology]]'' article.

==What to know more?==
Information about the site can be requested at: ''info@librepathology.org''

==Suggestions or corrections==
If you have suggestions or corrections send them to: ''fixit@librepathology.org''

==Editing==
If you are interested in editing send a brief self introduction to: ''gettinginvolved@librepathology.org''

==Media inquiries==
Media inquires should be sent to: ''info@librepathology.org''

==Copyright questions==
Issues related to copyright should be sent to: ''copyright@librepathology.org''

==Contact the site administrator==
The site administrator can be reached at: ''admin@librepathology.org''

==See also==
*[[Libre Pathology:Contributing]].
*[[Libre Pathology:Copyrights]].
*[[Libre Pathology:Editing]].
*[[Libre Pathology:Manual of style]].

[[Category:Libre Pathology]]

__NOTOC__

Libre Pathology:Contact us

2016-05-04T05:05:20Z

Rudolf: /* Suggestions or corrections */

The page is about how to '''contact us'''. If you have a general question, the answer may be in the ''[[Libre Pathology]]'' article.

==What to know more?==
Information about the site can be requested at: ''info@librepathology.org''

==Suggestions or corrections==
If you have suggestions or corrections send them to: ''fixit@librepathology.org''

==Editing==
If you are interested in editing send a brief self introduction to: ''gettinginvolved@librepathology.org''

==Media inquiries==
Media inquires should be sent to: ''info@librepathology.org''

==Copyright questions==
Issues related to copyright should be sent to: ''copyright@librepathology.org''

==Contact the site administrator==
The site administrator can be reached at: ''admin@librepathology.org''

==See also==
*[[Libre Pathology:Copyrights]].
*[[Libre Pathology:Editing]].
*[[Libre Pathology:Manual of style]].

[[Category:Libre Pathology]]

__NOTOC__

Talk:Papillary adenoma of the kidney

2016-05-04T00:46:09Z

Rudolf: Created page with "Can be clear cell... http://www.hindawi.com/journals/au/2008/974848/"

Can be clear cell... http://www.hindawi.com/journals/au/2008/974848/

MediaWiki:Sitenotice

2016-04-22T01:06:00Z

Rudolf: survey

<center><big>'''Please take a moment to complete [https://pathologyprotocols.org/limesurvey/index.php/448969?lang=en a short survey] to help improve Libre Pathology.'''</big></center>

User talk:Emily P

2016-02-10T05:16:03Z

Rudolf: Rudolf moved page User talk:Emily to User talk:Emily P: Automatically moved page while renaming the user "Emily" to "Emily P"

Welcome to [[Libre Pathology]]!

Here are a few useful pages on editing:
*[[Help:How to edit]] - describes the wiki mark-up.
*[[LP:Format]] - describes the format of the site.
*[[LP:References]] - shows how references are done.
*[[LP:Sandbox]] - a place to try edits.

Some guidelines:
*[[LP:Be bold]] - just try it out!
*[[LP:Verifiability]] - what to use for references.
*[[LP:No original research]] - Libre Pathology is ''not'' a primary source.
*[[LP:Neutral point of view]] - articles dealing with controversial areas should ''not'' take sides.

By the way, you can sign your name on Talk pages and Discussion pages using three tildes,
like this: [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]). Four tildes ([[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 00:42, 24 July 2015 (EDT))
produces your name and the current date. If you have any questions, ask me on [[User talk:Michael|my talk page]]. [[User:Rudolf|Rudolf]] ([[User talk:Rudolf|talk]]) 00:42, 24 July 2015 (EDT)

Lung cancer staging

2015-10-26T02:22:40Z

Rudolf:

The article deals with '''lung cancer staging'''. A general discussion of staging is found in ''[[cancer staging]]''.

==General==
The clinical staging and pathologic staging are concordant in only approximately ~50% of cases.<ref name=pmid15734416>{{Cite journal | last1 = López-Encuentra | first1 = A. | last2 = García-Luján | first2 = R. | last3 = Rivas | first3 = JJ. | last4 = Rodríguez-Rodríguez | first4 = J. | last5 = Torres-Lanza | first5 = J. | last6 = Varela-Simo | first6 = G. | title = Comparison between clinical and pathologic staging in 2,994 cases of lung cancer. | journal = Ann Thorac Surg | volume = 79 | issue = 3 | pages = 974-9; discussion 979 | month = Mar | year = 2005 | doi = 10.1016/j.athoracsur.2004.06.004 | PMID = 15734416 }}</ref>

==TNM staging system==

===Tumour===
{| class="wikitable sortable"
!T stage
!Size/criteria
!Other requirements
!Comment
|-
| T0
| (no tumour)
|
| rare
|-
| Tis
|
| no invasion
| rare
|-
| T1a
| <=2 cm
| confined to lung, no [[VPI]], no main branch bronchus involvement
|
|-
| T1b
| >2 cm, <=3 cm
| confined to lung, no [[VPI]], no main branch bronchus involvement
|
|-
| T2a
| >3cm ''or'' VPI ''or'' main branch bronchus involvement, <= 5cm
| confined to lung, no total lung collapse
|
|-
| T2b
| >5cm ''or'' VPI ''or'' main branch bronchus involvement, < 7cm
| confined to lung, no total lung collapse
|
|-
| T3
| >7 cm ''or'' 2 or more nodules ''or'' total lung collapse
|
|
|-
| T4
| extension beyond the lung
|
|
|}

==See also==
*[[Lung tumours]].

==References==
{{Reflist|1}}

==External links==
*[http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-staging Lung cancer staging (cancer.org)].

[[Category:Pulmonary pathology]]
[[Category:Cancer staging]]

Lung cancer staging

2015-10-26T02:22:12Z

Rudolf:

The article deals with '''lung cancer staging'''. A general discussion of staging is found in ''[[cancer staging]]''.

==General==
The clinical staging and pathologic staging are concordant in only approximately ~50% of cases.<ref name=pmid15734416>{{Cite journal | last1 = López-Encuentra | first1 = A. | last2 = García-Luján | first2 = R. | last3 = Rivas | first3 = JJ. | last4 = Rodríguez-Rodríguez | first4 = J. | last5 = Torres-Lanza | first5 = J. | last6 = Varela-Simo | first6 = G. | title = Comparison between clinical and pathologic staging in 2,994 cases of lung cancer. | journal = Ann Thorac Surg | volume = 79 | issue = 3 | pages = 974-9; discussion 979 | month = Mar | year = 2005 | doi = 10.1016/j.athoracsur.2004.06.004 | PMID = 15734416 }}</ref>

==TNM staging system==

===Tumour===
{| class="wikitable sortable"
!T stage
!Size/criteria
!Other requirements
!Comment
|-
| T0
| (no tumour)
|
| rare
|-
| Tis
|
| no invasion
| rare
|-
| T1a
| <=2 cm
| confined to lung, no [[VPI]], no main branch bronchus involvement
|
|-
| T1b
| >2 cm, <=3 cm
| confined to lung, no [[VPI]], no main branch bronchus involvement
|
|-
| T2a
| >3cm ''or'' VPI ''or'' main branch bronchus involvement, <= 5cm
| confined to lung, no total lung collapse
|
|-
| T2b
| >5cm ''or'' VPI ''or'' main branch bronchus involvement, < 7cm
| confined to lung, no total lung collapse
|
|-
| T3
| >7 cm ''or'' 2 or more nodules ''or'' total lung collapse
|
|
|-
| T4
| extension beyond the lung
|
|
|}

==See also==
*[[Lung tumours]].

==External links==
*[http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-staging Lung cancer staging (cancer.org)].

[[Category:Pulmonary pathology]]
[[Category:Cancer staging]]

Case 112

2015-09-24T18:32:58Z

Rudolf: /* Diagnosis */

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION.</center>
<br>The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.<ref name=pmid24441661>{{Cite journal | last1 = Maniar | first1 = KP. | last2 = Wang | first2 = Y. | last3 = Visvanathan | first3 = K. | last4 = Shih | first4 = IeM. | last5 = Kurman | first5 = RJ. | title = Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: a morphologic and immunohistochemical analysis of 37 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 743-55 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000155 | PMID = 24441661 }}</ref> These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. <ref name=pmid25188864>{{Cite journal | last1 = Zeppernick | first1 = F. | last2 = Ardighieri | first2 = L. | last3 = Hannibal | first3 = CG. | last4 = Vang | first4 = R. | last5 = Junge | first5 = J. | last6 = Kjaer | first6 = SK. | last7 = Zhang | first7 = R. | last8 = Kurman | first8 = RJ. | last9 = Shih | first9 = IeM. | title = BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors. | journal = Am J Surg Pathol | volume = 38 | issue = 12 | pages = 1603-11 | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000313 | PMID = 25188864 }}</ref>

====References====
{{Reflist|1}}

}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case 112

2015-09-24T18:32:34Z

Rudolf:

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION.</center>
<br>The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.<ref name=pmid24441661>{{Cite journal | last1 = Maniar | first1 = KP. | last2 = Wang | first2 = Y. | last3 = Visvanathan | first3 = K. | last4 = Shih | first4 = IeM. | last5 = Kurman | first5 = RJ. | title = Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: a morphologic and immunohistochemical analysis of 37 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 743-55 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000155 | PMID = 24441661 }}</ref> These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. <ref name=PMID 25188864> {{Cite journal | last1 = Zeppernick | first1 = F. | last2 = Ardighieri | first2 = L. | last3 = Hannibal | first3 = CG. | last4 = Vang | first4 = R. | last5 = Junge | first5 = J. | last6 = Kjaer | first6 = SK. | last7 = Zhang | first7 = R. | last8 = Kurman | first8 = RJ. | last9 = Shih | first9 = IeM. | title = BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumors. | journal = Am J Surg Pathol | volume = 38 | issue = 12 | pages = 1603-11 | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000313 | PMID = 25188864 }}</ref>

====References====
{{Reflist|1}}

}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case 112

2015-09-24T18:24:10Z

Rudolf: /* Diagnosis */

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION.</center>
<br>The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.<ref name=pmid24441661>{{Cite journal | last1 = Maniar | first1 = KP. | last2 = Wang | first2 = Y. | last3 = Visvanathan | first3 = K. | last4 = Shih | first4 = IeM. | last5 = Kurman | first5 = RJ. | title = Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: a morphologic and immunohistochemical analysis of 37 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 743-55 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000155 | PMID = 24441661 }}</ref> These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. (Am J Surg Pathol 2014;38:1603–1611)

====References====
{{Reflist|1}}

}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case 112

2015-09-24T18:23:39Z

Rudolf: /* Diagnosis */

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION.</center>
<br>The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.<ref name=pmid24441661>{{Cite journal | last1 = Maniar | first1 = KP. | last2 = Wang | first2 = Y. | last3 = Visvanathan | first3 = K. | last4 = Shih | first4 = IeM. | last5 = Kurman | first5 = RJ. | title = Evaluation of microinvasion and lymph node involvement in ovarian serous borderline/atypical proliferative serous tumors: a morphologic and immunohistochemical analysis of 37 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 743-55 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000155 | PMID = 24441661 }}</ref>. These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. (Am J Surg Pathol 2014;38:1603–1611)

====References====
{{Reflist|1}}

}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case 112

2015-09-24T18:19:25Z

Rudolf: /* Diagnosis */

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION.</center>
<br>The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.(Am J Surg Pathol 2014;38:743–755). These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. (Am J Surg Pathol 2014;38:1603–1611) ( </center>}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case:112

2015-09-24T18:17:07Z

Rudolf: Rudolf moved page Case:112 to Case 112: move to standard

#REDIRECT [[Case 112]]

Case 112

2015-09-24T18:17:06Z

Rudolf: Rudolf moved page Case:112 to Case 112: move to standard

===Provided clinical history===
42 year old woman with a 9 cm ovarian mass

===Site===
ZZZ

===Primary image===
[[Image: Gross of borderline serous tumor of the ovary 01.jpg|500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Low maginification of borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Intermediate magnification of a borderline serous tumor showing eosiniophilic cells.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Microinvasion in a borderline serous tumor of the ovary.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>SEROUS CYSTADENOFIBROMA OR ENDOCERVICAL TYPE BORDERLINE MUCINOUS TUMOR OR PAPILLARY CLEAR CELL CARCINOMA SIMULATING BORDERLINE TUMOR </center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>CONSIDER DOING IMMUNO STAINS ?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr= POSITIVE
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1= POSITIVE
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>BORDERLINE SEROUS TUMOR OF THE OVARY WITH MICROINVASION. The characteristic feature of borderline serous tumor is the hierarchical branching of the papillae, where the papillae progressively branch from larger ones to smaller one and finally into tufts of epithelial cells. The cells show only mild to moderate atypia. A cytadenofibroma may have similar proliferation, but by convention should be less than 5% of the tumor. Focal mucinous change may also occur. Papillary clear cell carcinoma simulating borderline tumor will show a WT1-ve, ER-ve, PR-ve immunoprofile in contrast to the positive profile of the serous tumor. Often clusters of cells with abundant eosinophilic cytoplasm are seen at the surface of papillae (star, image 2; oval image 3) or in lymphatic like spaces either as single cells or small papillary clusters. This theoretically represents microinvasion which is variably defined by different authors (<3 or 5 mm or 10mm2). However, recent evidence suggests that the two patterns of invasion have vastly different prognosis. The AEC (abundant eosinophilic cells) are p16 positive and reflect a terminally differentiated senescent phenotype. If invasion is exclusively composed of this cell type, then these do not portend a poor prognosis.(Am J Surg Pathol 2014;38:743–755). These cells are significantly more often seen in BRAF mutated tumors, and are perhaps associated with a better prognosis. (Am J Surg Pathol 2014;38:1603–1611) ( </center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case111

2015-09-24T18:15:51Z

Rudolf: Rudolf moved page Case111 to Case 111

#REDIRECT [[Case 111]]

Case 111

2015-09-24T18:15:50Z

Rudolf: Rudolf moved page Case111 to Case 111

===Provided clinical history===
28 year old woman with a positive pregnancy test. Cornual mass on ultrasound. No fetal heart identified.

===Site===
Pregnancy

===Primary image===
[[Image: Ariasstella changes in endometrium 4x.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Ariasstella changes in endometrium 20x.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>CLEAR CELL CARCINOMA</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta= POSITIVE
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>ARIAS STELLA CHANGES/REACTION. The diagnosis in this case is straightforward and relatively easy in this very young patient with a positive pregnancy test. However, it can be challenging in an older patient who comes in with bleeding. Arias Stella reaction shows endometrial glands lined by clear cells with atypia. Intranuclear inclusions (arrow) are often present. There can be occasional mitotic activity, which can further heighten its mimicry to clear cell carcinoma. Furthermore, the clear cells of Arias Stella are positive for Napsin and HNF1Beta, markers that are positive in clear cell carcinoma. AMACR is reportedly negative in Arias Stella while being positive in clear cell carcinoma although too few cases are tested to be confident of this claim. </center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 2]]

Case:Blank

2015-09-24T18:07:33Z

Rudolf: /* IHC */ +add napsin

===Provided clinical history===
XXX year old man/woman, YYY

===Site===
ZZZ

===Primary image===
[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| napsin=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Case 96

2015-09-20T20:49:11Z

Rudolf:

===Provided clinical history===
43 year old woman, renal mass

===Site===
Left kidney

===Primary image===
[[Image: Hereditary leiomyomatosis and renal cell carcinoma associated RCC -- low mag.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Hereditary leiomyomatosis and renal cell carcinoma associated RCC -- intermed mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Hereditary leiomyomatosis and renal cell carcinoma associated RCC -- high mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[Papillary renal cell carcinoma]], [[Unclassified renal cell carcinoma]], [[HLRCC|HLRCC-associated renal cell carcinoma]], Familial papillary renal cell carcinoma, Translocation carcinoma</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>hysterectomy for fibroids when 33 years old, skin rash. Brother diagnosised with PaRCC when 41 years old - died 1 year later. Uncle died of RCC is 40s.</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>Smells syndromic. I'd bet the "skin rash" is leiomyomas.</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10= '''NEGATIVE'''
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20= '''NEGATIVE'''
| ck34be12=
| ck5_6=
| ck7= '''NEGATIVE'''
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fh= '''NEGATIVE''' in tumour
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8= '''POSITIVE'''
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3= '''NEGATIVE'''
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[Hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]]</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]

[[Category:Cases in genitourinary pathology]]
[[Category:Cases in genitourinary pathology - senior]]
[[Category:Cases difficulty 5]]

Case:Blank

2015-09-20T20:48:05Z

Rudolf: +fh -- update IHC template

===Provided clinical history===
XXX year old man/woman, YYY

===Site===
ZZZ

===Primary image===
[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fh=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Case 81

2015-09-19T22:18:23Z

Rudolf: /* IHC */

===Provided clinical history===
72 year old woman, hematuria

===Site===
Urinary bladder

===Primary image===
[[Image: Adenocarcinoma_of_the_urinary_bladder_--_low_mag.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Adenocarcinoma_of_the_urinary_bladder_--_intermed_mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Adenocarcinoma_of_the_urinary_bladder_--_high_mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[urothelial carcinoma]] with glandular differentiation, [[adenocarcinoma of the urinary bladder]], [[urachal carcinoma]], metastatic [[colorectal adenocarcinoma]]</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>no personal history of cancer, father died of rectal cancer, healthy brother, sister with a history of GI polyps, mildly obese, smoked when in her 20s, cytoscopy shows a lesion on left lateral wall of the bladder</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>It's an adenocarcinoma. Beta-catenin is give you the answer!</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin= [[Image:Adenocarcinoma of the urinary bladder - beta-catenin -- very high mag.jpg |300px|link=|center|beta-catenin IHC]]
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2= '''POSITIVE'''
| cea=
| chromo=
| chromo=
| ck17=
| ck19=
| ck20= '''POSITIVE'''
| ck34be12=
| ck5_6=
| ck7= '''POSITIVE'''
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gata3= '''POSITIVE'''
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Chromosomal translocations====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[primary adenocarcinoma of the urinary bladder]]</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]

[[Category:Cases in genitourinary pathology]]
[[Category:Cases in genitourinary pathology - senior]]
[[Category:Cases difficulty 5]]

GATA3

2015-09-19T22:17:14Z

Rudolf:

'''GATA3''' an [[immunostain]] that is increasingly used in [[genitourinary pathology]].

Positive:
*[[Urothelial carcinoma]].<ref name=pmid22982890>{{cite journal |author=Chang A, Amin A, Gabrielson E, ''et al.'' |title=Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung |journal=Am. J. Surg. Pathol. |volume=36 |issue=10 |pages=1472–6 |year=2012 |month=October |pmid=22982890 |pmc=3444740 |doi=10.1097/PAS.0b013e318260cde7 |url=}}</ref>
*[[Lobular breast carcinoma]].<ref name=pmid24061521>{{Cite journal | last1 = Ellis | first1 = CL. | last2 = Chang | first2 = AG. | last3 = Cimino-Mathews | first3 = A. | last4 = Argani | first4 = P. | last5 = Youssef | first5 = RF. | last6 = Kapur | first6 = P. | last7 = Montgomery | first7 = EA. | last8 = Epstein | first8 = JI. | title = GATA-3 immunohistochemistry in the differential diagnosis of adenocarcinoma of the urinary bladder. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1756-60 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e31829cdba7 | PMID = 24061521 }}</ref>

Negative:
*[[Prostate carcinoma]].
*[[Squamous cell carcinoma of the lung]].<ref name=pmid22982890>{{Cite journal | last1 = Chang | first1 = A. | last2 = Amin | first2 = A. | last3 = Gabrielson | first3 = E. | last4 = Illei | first4 = P. | last5 = Roden | first5 = RB. | last6 = Sharma | first6 = R. | last7 = Epstein | first7 = JI. | title = Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung. | journal = Am J Surg Pathol | volume = 36 | issue = 10 | pages = 1472-6 | month = Oct | year = 2012 | doi = 10.1097/PAS.0b013e318260cde7 | PMID = 22982890 }}</ref>

===Images===
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444740/figure/F1/ GATA3 nuclear staining - urothelial carcinoma (nih.gov)].<ref name=pmid22982890>{{Cite journal | last1 = Chang | first1 = A. | last2 = Amin | first2 = A. | last3 = Gabrielson | first3 = E. | last4 = Illei | first4 = P. | last5 = Roden | first5 = RB. | last6 = Sharma | first6 = R. | last7 = Epstein | first7 = JI. | title = Utility of GATA3 immunohistochemistry in differentiating urothelial carcinoma from prostate adenocarcinoma and squamous cell carcinomas of the uterine cervix, anus, and lung. | journal = Am J Surg Pathol | volume = 36 | issue = 10 | pages = 1472-6 | month = Oct | year = 2012 | doi = 10.1097/PAS.0b013e318260cde7 | PMID = 22982890 }}</ref>

==See also==
*[[Immunohistochemistry]].

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry]]

Case 84

2015-09-19T22:10:27Z

Rudolf: /* Diagnosis */

===Provided clinical history===
72 year old man

===Site===
Prostate gland

===Primary image===
[[Image: Sarcomatoid prostate carcinoma -- low mag.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Sarcomatoid prostate carcinoma -- intermed mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Sarcomatoid prostate carcinoma -- high mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>[[fibrosarcoma]], [[sarcomatoid urothelial carcinoma]], [[sarcomatoid prostate carcinoma]], metastatic [[sarcomatoid carcinoma]], [[pleomorphic undifferentiated sarcoma]]</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>Core biopsies 5 years ago had Gleason 6/10 in 2 cores, 5% of tissue, presented 1 month ago with gross hematuria, PSA 9.3 - up from 6.2 one year ago</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>Looks like a sarcomatoid changes... and funny looking glands. Not that hard.</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20= '''NEGATIVE'''
| ck34be12=
| ck5_6= '''NEGATIVE'''
| ck7= '''POSITIVE''' in glandular areas, rare staining in spindled areas
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gata3= '''NEGATIVE'''
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63= '''NEGATIVE'''
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa= '''POSITIVE''' in glands, '''NEGATIVE''' in spindled areas
| psap= '''POSITIVE''' in glands, weak blush in spindled areas
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim= glands '''NEGATIVE''', spindle cells '''POSITIVE'''
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[sarcomatoid prostate carcinoma]]</center>}}
<br>

===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Case:Blank

2015-09-19T22:09:14Z

Rudolf: /* IHC */

===Provided clinical history===
XXX year old man/woman, YYY

===Site===
ZZZ

===Primary image===
[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| atrx=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| ca9=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cathepsink=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gata3=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| ini1=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| map2=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| nf=
| nkx3_1=
| nse=
| oct3_4=
| p16=
| p501s=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| tfeb=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Case 59

2015-09-19T19:08:38Z

Rudolf: /* Chromosomal translocations */ +clonality testing

===Provided clinical history===
73 year old woman, sigmoidectomy for foreign body perforation

===Site===
lymph node from sigmoidectomy specimen

===Primary image===
[[Image: Chronic lymphocytic leukemia - low mag.jpg |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: Chronic lymphocytic leukemia - intermed mag.jpg |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: Chronic lymphocytic leukemia - high mag.jpg |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>Chicken bone lead to sigmoid perforation. Large lymph node found during operation - sent to pathology. Mild leukocytosis.</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>Could be neoplastic... did you do stains?</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2= '''POSITIVE'''
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10= '''NEGATIVE'''
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20= '''POSITIVE'''
| cd21=
| cd23= '''POSITIVE'''
| cd3= mostly '''NEGATIVE'''
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45= '''POSITIVE'''
| cd45=
| cd5= '''POSITIVE'''
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1= '''NEGATIVE'''
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone = Clonality '''PRESENT'''
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone = Clonality '''ABSENT'''
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[Small lymphocytic lymphoma]]</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]

[[Category:Cases in hematopathology]]
[[Category:Cases in hematopathology - junior]]
[[Category:Cases in lymph node pathology]]
[[Category:Cases in lymph node pathology - junior]]

[[Category:Cases difficulty 3]]

Case 11

2015-09-19T19:07:01Z

Rudolf: /* IHC */

===Clinical history===
57 year old woman. Multi-organ dysfunction and stroke.

===Primary image===
[[Image:Intravascular_lymphoma_-_intermed_mag.jpg|500px|link=|center|]]
<center>Pons. Intermediate magnification. [[H&E stain]].</center>

{{hidden|High magnification|[[Image:Intravascular_lymphoma_-_high_mag.jpg|500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

{{hidden|Very high magnification|[[Image:Intravascular_lymphoma_-_very_high_mag.jpg|500px|link=|center|]]
<center>Very high magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>leukemia (blast crisis)</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>WBC significantly elevated.</center>}}

====Ask a friend====
{{hidden|Ask a friend|<center>It looks intravascular and lymphoid.</center>}}

====Stains====
{{Case Stains
| blank=Dr T would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
}}

====IHC====
{{Case IHC
| blank=Dr T would ask why!
| ae1ae3=
| a1at=
| acth=
| afp=
| alk1=
| amacr=
| b2microgl=
| b723=
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcit=
| calponin=
| calretinin=
| cd10=
| cd117=
| cd15=
| cd1a=
| cd20= '''POSITIVE'''
| cd21=
| cd23=
| cd3= '''NEGATIVE'''
| cd30=
| cd31=
| cd34= '''NEGATIVE'''
| cd35=
| cd4=
| cd43=
| cd45= '''POSITIVE'''
| cd5=
| cd56=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cea=
| chromo=
| ck19=
| ck20=
| ck34be12=
| ck7=
| cmv=
| cmyc=
| cyclind1=
| desmin=
| ebv=
| ema=
| erpr=
| fascin=
| fsh=
| fviii=
| fxiiia=
| gastrin=
| gcdfp=
| gh=
| glucag=
| hbme1=
| hbvc=
| hbvs=
| hcg=
| hepatocyte=
| her2=
| hmb45=
| hpv=
| hsv1=
| hsv2=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| lca= '''POSITIVE'''
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| melanina=
| myleoperox=
| myod1=
| myog=
| myog=
| nse=
| p53=
| p63=
| panker=
| pcna=
| plap=
| pnl2c=
| prolac=
| psa=
| s100=
| sma=
| somatsat=
| synapto=
| tdt=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulexeurope=
| vim=
| vip=
| vzv=
}}

====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone = Clonality '''PRESENT'''
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone = Clonality '''ABSENT'''
}}

===Diagnosis===
{{hidden|Diagnosis|<center>[[Intravascular lymphoma|Intravascular large B-cell lymphoma]].</center><br>Comment:<br>This uncommon lymphoma is not infrequently an autopsy diagnosis.}}
<br>
===Other cases===
{{Cases navigation|state=collapsed}}

__NOTOC__

[[Category:Cases]]
[[Category:Cases in neuropathology]]
[[Category:Cases in hematopathology]]
[[Category:Cases in autopsy pathology]]

[[Category:Cases difficulty 4]]
[[Category:Cases in neuropathology - senior]]
[[Category:Cases in hematopathology - senior]]
[[Category:Cases in autopsy pathology - senior]]

Case:Blank

2015-09-19T19:05:22Z

Rudolf: /* Molecular testing */

===Provided clinical history===
XXX year old man/woman, YYY

===Site===
ZZZ

===Primary image===
[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}
====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}
=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Case:Blank

2015-09-19T19:05:08Z

Rudolf: /* Chromosomal translocations */

===Provided clinical history===
XXX year old man/woman, YYY

===Site===
ZZZ

===Primary image===
[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Low magnification. [[H&E stain]].</center>

{{hidden|Intermediate magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>Intermediate magnification. [[H&E stain]].</center>}}

{{hidden|High magnification|[[Image: NAME OF IMAGE GOES HERE |500px|link=|center|]]
<center>High magnification. [[H&E stain]].</center>}}

===Differential diagnosis===
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}}

===Additional tests===
====More history====
{{hidden|More history|<center>MORE HISTORY HERE</center>}}

====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}

====Stains====
{{Case Stains
| blank=Dr Torres would ask why!
| alcpas=
| alc1=
| alc25=
| aur=
| biel=
| bili=
| iron=
| congored=
| cresylv=
| dieterle=
| diffquik=
| fontana=
| gallyas=
| giemsa=
| gms=
| gomori=
| gram=
| gremelius=
| jms=
| jones=
| kinyoun=
| luxol=
| masson=
| mmas=
| movat=
| mucicar=
| oilredo=
| orecein=
| pas=
| pasd=
| pasf=
| ptah=
| prussian=
| reticulin=
| sudanblackb=
| toluidine=
| verhoeff=
| vonkossa=
| warthinstarry=
| zn=
}}
====IHC====
{{Case IHC
| blank=Dr Torres would ask why!
| a1at=
| acth=
| ae1ae3=
| afp=
| alk1=
| amacr=
| ar=
| b2microglobulin=
| b72_3=
| bcatenin=
| bcl2=
| bcl6=
| bclxl=
| c3=
| calcitonin=
| calponin=
| calretinin=
| cam5p2=
| cd10=
| cd117=
| cd138=
| cd15=
| cd1a=
| cd20=
| cd21=
| cd23=
| cd3=
| cd30=
| cd31=
| cd34=
| cd35=
| cd4=
| cd43=
| cd45=
| cd45=
| cd5=
| cd56=
| cd57=
| cd68=
| cd7=
| cd79a=
| cd8=
| cd99=
| cdx2=
| cea=
| chromo=
| chromo=
| ck17=
| ck19=
| ck20=
| ck34be12=
| ck5_6=
| ck7=
| cmv=
| cmyc=
| cyclin_d1=
| d2_40=
| desmin=
| dog1=
| ebv=
| ema=
| erpr=
| f_viii=
| f_xiiia=
| fascin=
| fsh=
| gastrin=
| gcdfp=
| gfap=
| gh=
| glucagon=
| glypican3=
| hbme1=
| hbv_core=
| hbv_surf=
| hcaldesmon=
| hcg=
| helicobacter=
| hepatocyte=
| her2=
| hhv8=
| hmb45=
| hnf1beta=
| hpv=
| hsv1=
| hsv2=
| Idh-1=
| inhibin=
| insulin=
| kappa=
| ki67=
| lambda=
| leu7=
| lga=
| lgg=
| lgm=
| lh=
| lysozyme=
| mammogl=
| mcv=
| melanin_a=
| mitf=
| mum1=
| myleoperox=
| myo_d1=
| myog=
| myog=
| nf=
| nse=
| oct3_4=
| p16=
| p53=
| p57=
| p63=
| panker=
| pax2=
| pax5=
| pax8=
| pcna=
| pdgfr=
| plap=
| pnl-2c=
| prolactin=
| psa=
| psap=
| rcc=
| s100=
| sma=
| somatsatin=
| synapto=
| tdt=
| tfe3=
| thyrogl=
| toxopl=
| tsh=
| ttf1=
| ubiquitin=
| uchl1=
| ulex_europe=
| vim=
| vip=
| vzv=
| wt1=
}}
====Molecular testing====
=====Chromosomal translocations=====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t2_13=
| t8_14=
| t9_22bcr_abl=
| t9_22chn_ews=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t21_22=
| tx_1=
| tx_17=
| tx_18=
}}

=====Other molecular tests=====
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}

===Diagnosis===
{{hidden|Diagnosis|<center>DIAGNOSIS GOES HERE</center>}}
<br>
===Other cases===
{{Cases navigation}}

__NOTOC__

[[Category:Cases]]



[[Category:Cases difficulty 4]]

Template:Case Molecular

2015-09-19T19:04:10Z

Rudolf:

<table>
<tr>
<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests (A-B)</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>ALK sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{alk| }}} | {{{alk}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / [[PCR]] </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>BRAF [[DNA sequencing|sequencing]]</td><td class="mw-collapsible mw-collapsed">{{#if:{{{braf| }}} | {{{braf}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests (C-H)</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>EGRF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{egrf| }}} | {{{egrf}}} | {{{blank}}} }}</td></tr>
<tr><td>H3F3A sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{h3f3a| }}} | {{{h3f3a}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests (I-J)</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>[[identity testing|Identity testing]] PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{identity_test| }}} | {{{identity_test}}} | {{{blank}}} }}</td></tr>
<tr><td>IDH1/2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{idh1_2| }}} | {{{idh1_2}}} | {{{blank}}} }}</td></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests (K-Z)</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>KIT sequencing </td><td class="mw-collapsible mw-collapsed">{{#if:{{{kit| }}} | {{{kit}}} | {{{blank}}} }}</td></tr>
<tr><td>LOH 1p/19q PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{loh_1p19q| }}} | {{{loh_1p19q}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>
<noinclude>

<pre>
{{Case Molecular
| blank=Dr Torres would ask why!
| alk =
| b_cell_clone =
| bcl2 =
| braf =
| EBV_pcr =
| egrf =
| h3f3a =
| hhv8_pcr =
| identity_test =
| idh1_2 =
| jak2_v617f =
| kit =
| loh_1p19q =
| t_cell_clone =
}}
</pre>

==See also==
*[[:Template:Hide]].
*[[:Template:Case IHC]].
*[[:Template:Case Stains]].
*[[:Template:Case Translocations]].
*[[Case:Notes]].

[[Category:Cases]]
</noinclude>

Template:Case Molecular

2015-09-19T15:39:27Z

Rudolf: create

<table>
<tr>
<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>LOH 1p/19q PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{loh_1p19q| }}} | {{{loh_1p19q}}} | {{{blank}}} }}</td></tr>
<tr><td>IDH1/2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{Idh1_2| }}} | {{{Idh1_2}}} | {{{blank}}} }}</td></tr>
<tr><td>BRAF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{braf| }}} | {{{braf}}} | {{{blank}}} }}</td></tr>
<tr><td>KIT sequencing </td><td class="mw-collapsible mw-collapsed">{{#if:{{{kit| }}} | {{{kit}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>More molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>H3F3A sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>EGRF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>ALK sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Heme molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>More heme molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>
</tr>
</table>
<noinclude>

<pre>
{{Case Translocations
| blank=Dr Torres would ask why!
| loh_1p19q =
| Idh1_2 =
| braf =
| kit =
| h3f3a =
| egrf =
| alk =
| bcl2 =
| t_cell_clone =
| b_cell_clone =
| jak2_v617f =
| EBV_pcr =
| hhv8_pcr =
}}
</pre>

==See also==
*[[:Template:Hide]].
*[[:Template:Case IHC]].
*[[:Template:Case Stains]].
*[[:Template:Case Translocations]].
*[[Case:Notes]].

[[Category:Cases]]
</noinclude>

LP:Sandbox

2015-09-19T15:34:05Z

Rudolf: /* Test 3 */ create

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 3==
<table><tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>LOH 1p/19q PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{loh_1p19q| }}} | {{{loh_1p19q}}} | {{{blank}}} }}</td></tr>
<tr><td>IDH1/2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{Idh1_2| }}} | {{{Idh1_2}}} | {{{blank}}} }}</td></tr>
<tr><td>BRAF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{braf| }}} | {{{braf}}} | {{{blank}}} }}</td></tr>
<tr><td>KIT sequencing </td><td class="mw-collapsible mw-collapsed">{{#if:{{{kit| }}} | {{{kit}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>More molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>H3F3A sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>EGRF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>ALK sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Heme molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>More heme molecular tests</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr></table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:29:14Z

Rudolf: /* Test 3 */

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 3==
<table><tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>LOH 1p/19q PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{loh_1p19q| }}} | {{{loh_1p19q}}} | {{{blank}}} }}</td></tr>
<tr><td>IDH1/2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{Idh1_2| }}} | {{{Idh1_2}}} | {{{blank}}} }}</td></tr>
<tr><td>BRAF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{braf| }}} | {{{braf}}} | {{{blank}}} }}</td></tr>
<tr><td>KIT sequencing </td><td class="mw-collapsible mw-collapsed">{{#if:{{{kit| }}} | {{{kit}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>H3F3A sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>EGRF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>ALK sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr></table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:28:21Z

Rudolf: /* Test 3 */

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 3==
<table><tr>
<th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>H3F3A sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>EGRF sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>ALK sequencing</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>

</tr></table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:27:52Z

Rudolf: /* Test 3 */

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 3==
<table><tr>
<th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>BCL2 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{bcl2| }}} | {{{bcl2}}} | {{{blank}}} }}</td></tr>
<tr><td>T cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t_cell_clone| }}} | {{{t_cell_clone}}} | {{{blank}}} }}</td></tr>
<tr><td>B cell clonality Southern / PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{b_cell_clone| }}} | {{{b_cell_clone}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr></table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:25:41Z

Rudolf: /* Test 2 */

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 3==
<table><tr>
<th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>JAK2 V617F ARMS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{jak2_v617f| }}} | {{{jak2_v617f}}} | {{{blank}}} }}</td></tr>
<tr><td>EBV PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{EBV_pcr| }}} | {{{EBV_pcr}}} | {{{blank}}} }}</td></tr>
<tr><td>HHV-8 PCR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{hhv8_pcr| }}} | {{{hhv8_pcr}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr></table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:21:49Z

Rudolf: /* Test 1 */

[[File:Granulocytic Dysplasia.jpg|thumb | Atypical granulocytic lineage cells in a patient with myelodysplasia.]][[Image:Atypical_ductal_hyperplasia_-_very_low_mag.jpg|thumb|[[Atypical ductal hyperplasia]]. Very low magnification. [[H&E stain]]. (WC/Nephron)]]

The '''sandbox''' is a test page.

This is a place where things can be tried.

A reference follows this sentence.<ref>This is a reference.</ref>

Another references follows this sentence.<ref>{{Cite journal | last1 = Bonert | first1 = M. | last2 = Saville | first2 = BA. | title = A non-dimensional analysis of hemodialysis. | journal = Open Biomed Eng J | volume = 4 | issue = | pages = 138-55 | month = | year = 2010 | doi = 10.2174/1874120701004010138 | PMID = 21673980 |URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111706/ }}</ref>
==Section==
This is another section.

[[tubular adenoma of the gastrointestinal tract|Tubular adenoma]]s are a precursor [[CRC]]<ref name=pmid25930481>{{Cite journal | last1 = Roloff | first1 = KA. | last2 = Brown | first2 = E. | last3 = Stepanyan | first3 = G. | last4 = Valenzuela | first4 = GR. | title = Timing of Indicated Repeat Cesarean Delivery Before 39 Weeks of Gestation [151]. | journal = Obstet Gynecol | volume = 125 Suppl 1 | issue = | pages = 52S | month = May | year = 2015 | doi = 10.1097/01.AOG.0000463691.56327.ae | PMID = 25930481 }}</ref>
[[File:Example.jpg]]

[[A brokennn link is here]].

[[File:link_to_nonexistant_file.jpg]]

==DOI==
doi:10.1038/ng.2868

[[doi:10.1038/ng.2868]]

==Test 1==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 11-13</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(11;14) CCND1-IGH </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_14| }}} | {{{t11_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) EWS-WT1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22dsrct| }}} | {{{t11_22dsrct}}} | {{{blank}}} }}</td></tr>
<tr><td>t(11;22) FLI1-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t11_22ews| }}} | {{{t11_22ews}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;15) ETV6-NTRK3 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_15| }}} | {{{t12_15}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) FUS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16afh| }}} | {{{t12_16afh}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;16) CHOP-TLS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_16liposar| }}} | {{{t12_16liposar}}} | {{{blank}}} }}</td></tr>
<tr><td>t(12;22) EWS-ATF1 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t12_22| }}} | {{{t12_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 14-22</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(14,18) IGH-BCL2 </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t14_18| }}} | {{{t14_18}}} | {{{blank}}} }}</td></tr>
<tr><td>t(15;17) PML-RARA </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t15_17| }}} | {{{t15_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(16;21) FUS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t16_21| }}} | {{{t16_21}}} | {{{blank}}} }}</td></tr>
<tr><td>t(17;22) COLA1-PDGFB </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t17_22| }}} | {{{t17_22}}} | {{{blank}}} }}</td></tr>
<tr><td>t(21;22) EWS-ERG </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t21_22| }}} | {{{t21_22}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>
<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==Test 2==
<table>
<tr>

<th><table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr 1-10</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(1;13) PAX7-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t1_13| }}} | {{{t1_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(2,13) PAX3-FKHR </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t2_13| }}} | {{{t2_13}}} | {{{blank}}} }}</td></tr>
<tr><td>t(8;14) MYC-IGH</td><td class="mw-collapsible mw-collapsed">{{#if:{{{t8_14| }}} | {{{t8_14}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) BCR-ABL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22bcr_abl| }}} | {{{t9_22bcr_abl}}} | {{{blank}}} }}</td></tr>
<tr><td>t(9;22) CHN-EWS </td><td class="mw-collapsible mw-collapsed">{{#if:{{{t9_22chn_ews| }}} | {{{t9_22chn_ews}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th><th>

<table class="wikitable mw-collapsible mw-collapsed"><tr><th>Translocations Chr X & Y</th></tr><tr><th><table class="wikitable sortable"><tr><th>Test</th> <th>Result</th></tr>
<tr><td>t(X;1) PRCC-TFE3</td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_1| }}} | {{{tx_1}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;17) TFE3-ASPL </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_17| }}} | {{{tx_17}}} | {{{blank}}} }}</td></tr>
<tr><td>t(X;18) SYT-SSX </td><td class="mw-collapsible mw-collapsed">{{#if:{{{tx_18| }}} | {{{tx_18}}} | {{{blank}}} }}</td></tr>
</table></th></tr></table></th>

</tr>
</table>

==See also==
*[[Sandbox]].

==References==
{{Reflist|1}}

[[Category:Stuff]]

LP:Sandbox

2015-09-19T15:14:24Z

Rudolf: /* DOI */

Template:NoImageNotes

2015-08-20T02:57:08Z

Rudolf: Protected "Template:NoImageNotes": template ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite))

<includeonly><span class="wpImageAnnotatorControl wpImageAnnotatorOff">{{{1|}}}</span></includeonly><noinclude>{{documentation}}</noinclude>

Template:NoImageNotes

2015-08-20T02:55:43Z

Rudolf: copied from WikiCommons - version 22:07, 14 January 2012‎

<includeonly><span class="wpImageAnnotatorControl wpImageAnnotatorOff">{{{1|}}}</span></includeonly><noinclude>{{documentation}}</noinclude>