Anus - Revision history

Michael: /* Sign out */

2022-04-06T16:29:26Z

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← Older revision		Revision as of 16:29, 6 April 2022
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	- Consistent with fistula tract (acutely and chronically inflamed		- Consistent with fistula tract (acutely and chronically inflamed
	squamous mucosa with subepithelial inflamed tract, skeletal muscle		squamous mucosa with subepithelial inflamed tract, skeletal muscle
	and fibrosed tissue).		and fibrosed tissue).
	- NEGATIVE for dysplasia and NEGATIVE for malignancy.		- NEGATIVE for dysplasia and NEGATIVE for malignancy.
	</pre>		</pre>

Michael: /* Anal fistula */

2022-04-06T16:28:32Z

Anal fistula

← Older revision		Revision as of 16:28, 6 April 2022
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	Submitted as "Perineal Fistula Tract", Excision:		Submitted as "Perineal Fistula Tract", Excision:
	- Consistent with fistula tract (acutely and chronically inflamed		- Consistent with fistula tract (acutely and chronically inflamed
	squamous mucosa with ~~underlying microabscess~~, skeletal muscle		squamous mucosa with subepithelial inflamed tract, skeletal muscle
	and fibrosed tissue).		and fibrosed tissue).
	- NEGATIVE for dysplasia and NEGATIVE for malignancy.		- NEGATIVE for dysplasia and NEGATIVE for malignancy.

Michael: /* Sign out */

2022-04-06T16:24:05Z

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← Older revision		Revision as of 16:24, 6 April 2022
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	<pre>		<pre>
	Submitted as "Perineal Fistula Tract", Excision:		Submitted as "Perineal Fistula Tract", Excision:
	- Consistent with fistula tract (acutely and chronically inflamed squamous mucosa		- Consistent with fistula tract (acutely and chronically inflamed
	with skeletal muscle and ~~fibrosis~~).		squamous mucosa with underlying microabscess, skeletal muscle
	- NEGATIVE for dysplasia and NEGATIVE for malignancy.		and fibrosed tissue).
			- NEGATIVE for dysplasia and NEGATIVE for malignancy.
	</pre>		</pre>

Michael: /* Sign out */

2022-04-06T16:21:57Z

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← Older revision		Revision as of 16:21, 6 April 2022
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	<pre>		<pre>
	Submitted as "Perineal Fistula Tract", Excision:		Submitted as "Perineal Fistula Tract", Excision:
	- Consistent with fistula tract (acutely/chronically inflamed squamous mucosa		- Consistent with fistula tract (acutely and chronically inflamed squamous mucosa
	with skeletal muscle and fibrosis).		with skeletal muscle and fibrosis).
	- NEGATIVE for dysplasia and NEGATIVE for malignancy.		- NEGATIVE for dysplasia and NEGATIVE for malignancy.

Michael: /* Sign out */

2022-04-06T16:21:42Z

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← Older revision		Revision as of 16:21, 6 April 2022
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	===Sign out===		===Sign out===
			<pre>
			Submitted as "Perineal Fistula Tract", Excision:
			- Consistent with fistula tract (acutely/chronically inflamed squamous mucosa
			with skeletal muscle and fibrosis).
			- NEGATIVE for dysplasia and NEGATIVE for malignancy.
			</pre>

			====Block letters====
	<pre>		<pre>
	PERIANAL TISSUE ("OPENING OF FISTULA"), EXCISION:		PERIANAL TISSUE ("OPENING OF FISTULA"), EXCISION:

Michael: /* Normal */

2016-06-16T02:44:33Z

Normal

← Older revision		Revision as of 02:44, 16 June 2016
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	=Normal=		=Normal=
	{{Main\|Squamous metaplasia of the ~~rectum~~}}		*The dentate line (also known as the ''pectinate line'') divides the anal canal into upper two thirds and lower one third.
			*Typically, the squamocolumnar junction is just above the dentate line.

			Note:
			*Squamous epithelium 1 cm proximal to the dentate line is considered abnormal.<ref name=pmid11174313>{{Cite journal \| last1 = Bujanda \| first1 = L. \| last2 = Iriondo \| first2 = C. \| last3 = Muñoz \| first3 = C. \| last4 = Etxezarraga \| first4 = C. \| last5 = Ramírez \| first5 = MM. \| last6 = Ramos \| first6 = F. \| last7 = Sánchez \| first7 = A. \| title = Squamous metaplasia of the rectum and sigmoid colon. \| journal = Gastrointest Endosc \| volume = 53 \| issue = 2 \| pages = 255-6 \| month = Feb \| year = 2001 \| doi = \| PMID = 11174313 }}</ref>

			==Squamous metaplasia of the anus==
			{{Main\|Squamous metaplasia of the anus}}

	=Benign disease=		=Benign disease=

Michael at 02:19, 16 June 2016

2016-06-16T02:19:42Z

← Older revision		Revision as of 02:19, 16 June 2016
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	The '''anus''' occasionally shows-up on the pathologists desk. It sometimes comes with the rectum and [[colon]], as an abdominoperoneal resection (APR).		The '''anus''' occasionally shows-up on the pathologists desk. It sometimes comes with the rectum and [[colon]], as an abdominoperoneal resection (APR).

			=Normal=
			{{Main\|Squamous metaplasia of the rectum}}

	=Benign disease=		=Benign disease=

Michael: /* Anal intraepithelial neoplasia */

2016-05-06T14:25:03Z

Anal intraepithelial neoplasia

← Older revision		Revision as of 14:25, 6 May 2016
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	==Anal intraepithelial neoplasia==		==Anal intraepithelial neoplasia==
	*Abbreviated ''AIN''.		*Abbreviated ''AIN''.
	~~===General===~~		{{Main\|Anal intraepithelial lesions}}
	*Precursor lesion of anal [[squamous cell carcinoma]].
	*Usually [[HPV]] associated.
	**May be prevented by HPV vaccine.

	~~===Microscopic===~~		Note:
	~~DDx~~:		*The terminology changing to match the one now widely used for the [[uterine cervix]].
	*[[~~Anal squamous cell carcinoma]].~~

	~~====Grading====~~
	~~AIN is graded much like [[~~cervix~~\|cervical intraepithelial neoplasia~~]]:
	*High-grade anal intraepithelial neoplasia (HGAIN).
	*Low-grade anal intraepithelial neoplasia (LGAIN).

	~~===Sign out===~~
	~~<pre>~~
	~~ANAL CANAL, RIGHT UPPER QUADRANT, BIOPSY:~~
	~~- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION (CONDYLOMA ACUMINATUM-LIKE).~~
	~~</pre>~~

	~~<pre>~~
	~~ANAL CANAL, LEFT UPPER QUADRANT, BIOPSY:~~
	~~- LOW-GRADE SQUAMOUS INTRAEPITHELIAL LESION.~~
	~~- RECTAL MUCOSA WITHIN NORMAL LIMITS.~~
	~~</pre>~~

	~~<pre>~~
	~~SKIN LESION, PERIANAL, BIOPSY:~~
	~~- ANAL INTRAEPITHELIAL NEOPLASIA 3 (SEVERE DYSPLASIA), WARTY-TYPE.~~
	~~- MARGIN POSITIVE FOR ANAL INTRAEPITHELIAL NEOPLASIA 3.~~
	~~</pre>~~

	~~====Micro====~~
	~~There is dysplastic squamous epithelium with coarse chromatin, nuclear hyperchromasia,~~
	~~nuclear enlargement, irregular nuclear membranes, and an increase nuclear-to-cytoplasmic~~
	~~ratio. Mitotic activity is abundant. Several atypical mitoses are identified.~~

	~~The dysplastic squamous epithelium shows minimal maturation toward the surface (AIN 3). A~~
	~~sizable portion of the lesion show some maturation to the surface (AIN 2).~~

	~~Inflammation at the dermal-epidermal interface is minimal and the dermal-epidermal~~
	~~interface is well-demarcated. Focal ulceration is present.~~

	~~The margin of the biopsy has severely dysplastic epithelium (AIN 3)~~.

	=Anal cancer=		=Anal cancer=

Michael: /* Perianal abscess */

2016-04-27T13:14:24Z

Perianal abscess

← Older revision		Revision as of 13:14, 27 April 2016
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	==Anal wart==		==Anal wart==
	*See ''[[condyloma acuminatum]]''.		*See ''[[condyloma acuminatum]]''.

			==Pilonidal cyst==
			:Also ''pilonidal sinus'' and ''pilonidal disease''.
			{{Main\|Pilonidal cyst}}

	==Perianal abscess==		==Perianal abscess==

Michael: /* Anal intraepithelial neoplasia */

2015-03-19T18:08:48Z

Anal intraepithelial neoplasia

← Older revision		Revision as of 18:08, 19 March 2015
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	**May be prevented by HPV vaccine.		**May be prevented by HPV vaccine.

	===Grading===		===Microscopic===
			DDx:
			*[[Anal squamous cell carcinoma]].

			====Grading====
	AIN is graded much like [[cervix\|cervical intraepithelial neoplasia]]:		AIN is graded much like [[cervix\|cervical intraepithelial neoplasia]]:
	*High-grade anal intraepithelial neoplasia (HGAIN).		*High-grade anal intraepithelial neoplasia (HGAIN).