Calcific aortic stenosis - Revision history

Michael: /* See also */

2015-11-15T19:47:32Z

Michael: /* References */

2014-07-03T16:13:20Z

References

← Older revision		Revision as of 16:13, 3 July 2014
Line 106:		Line 106:
	{{Reflist\|2}}		{{Reflist\|2}}
	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Cardiovascular pathology]]

Michael at 14:50, 3 July 2014

2014-07-03T14:50:00Z

← Older revision		Revision as of 14:50, 3 July 2014
Line 47:		Line 47:
	*Syncope.		*Syncope.
	*Angina.		*Angina.
	*Dyspnea (shortness of breath) - first symptom.		*[[Dyspnea]] (shortness of breath) - first symptom.

	==Gross==		==Gross==

Michael: /* Images */

2014-06-05T01:21:26Z

Images

← Older revision		Revision as of 01:21, 5 June 2014
Line 71:		Line 71:

	===Images===		===Images===
			<gallery>
			Image: Calcific aortic stenosis -- very low mag.jpg \| CAS - very low mag.
			Image: Calcific aortic stenosis - alt -- very low mag.jpg \| CAS - very low mag.
			Image: Calcific aortic stenosis -- low mag.jpg \| CAS - low mag.
			Image: Calcific aortic stenosis -- intermed mag.jpg \| CAS - intermed. mag.

			Image: Calcific aortic stenosis - valve -- very low mag.jpg \| CAS - very low mag.
			Image: Calcific aortic stenosis - valve -- low mag.jpg \| CAS - very low mag.
			Image: Calcific aortic stenosis - valve - cropped -- low mag.jpg \| CAS - low mag.
			Image: Calcific aortic stenosis - valve -- intermed mag.jpg \| CAS - intermed. mag.
			</gallery>
	<gallery>		<gallery>
	File:Aortic valve stenosis, HE 1.jpg \| CAS. (WC/Patho)		File:Aortic valve stenosis, HE 1.jpg \| CAS. (WC/Patho)

Michael: +image

2014-06-05T01:19:27Z

+image

← Older revision		Revision as of 01:19, 5 June 2014
Line 1:		Line 1:
	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = ~~Aortic valve~~ stenosis~~, HE 2~~.jpg		\| Image = Calcific aortic stenosis -- very low mag.jpg
	\| Width =		\| Width =
	\| Caption = Aortic valve stenosis. [[H&E stain]].		\| Caption = Aortic valve stenosis. [[H&E stain]].

Michael at 17:54, 16 April 2014

2014-04-16T17:54:23Z

← Older revision		Revision as of 17:54, 16 April 2014
Line 48:		Line 48:
	*Angina.		*Angina.
	*Dyspnea (shortness of breath) - first symptom.		*Dyspnea (shortness of breath) - first symptom.

			==Gross==
			*Thickened, calcific appearing valve.

			Drop test:
			*Makes a "ting" sound when landing on a metal surface.

	==Microscopic==		==Microscopic==

Michael: /* Microscopic */

2014-04-16T17:52:08Z

Microscopic

← Older revision		Revision as of 17:52, 16 April 2014
Line 63:		Line 63:
	*[[Bicuspid aortic valve]].		*[[Bicuspid aortic valve]].
	*[[Rheumatic heart disease]].		*[[Rheumatic heart disease]].

			===Images===
			<gallery>
			File:Aortic valve stenosis, HE 1.jpg \| CAS. (WC/Patho)
			File:Aortic valve stenosis, HE 2.jpg \| CAS. (WC/Patho)
			File:Aortic valve stenosis, HE 3.jpg \| CAS. (WC/Patho)
			File:Aortic valve stenosis, HE 4.jpg \| CAS. (WC/Patho)
			File:Aortic valve stenosis, HE 5.jpg \| CAS. (WC/Patho)
			</gallery>

	==Sign out==		==Sign out==

Michael: split out

2014-04-16T17:50:46Z

split out

← Older revision		Revision as of 17:50, 16 April 2014
Line 1:		Line 1:
	~~#redirect~~ [[~~Heart_valves#Calcific_aortic_stenosis~~]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Aortic valve stenosis, HE 2.jpg
			\| Width =
			\| Caption = Aortic valve stenosis. [[H&E stain]].
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[infective endocarditis]] (may be a concurrent pathology), [[bicuspid aortic valve]],[[rheumatic heart disease]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = thickened calcified valve
			\| Grossing =
			\| Site = aortic valve - see ''[[heart valves]]''
			\| Assdx =
			\| Syndromes = [[bicuspid aortic valve]] if in younger individuals (50s)
			\| Clinicalhx =
			\| Signs = syncope
			\| Symptoms = dyspnea (usu. first symptom), angina
			\| Prevalence = common
			\| Bloodwork =
			\| Rads = thickened valve, reduced flow area, usu. no vegetation
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = [[infective endocarditis]], [[bicuspid aortic valve]], [[rheumatic heart disease]]
			\| Tx = valve replacement
			}}
			'''Calcific aortic stenosis''', abbreviated '''CAS''', is a very common disease of the aortic [[heart valves\|valve]]. It typically afflicts the elderly.

			In younger individuals the valve is typically abnormal ([[bicuspid aortic valve]] or unicuspid aortic valve).

			==General==
			*Somewhat similar to [[atherosclerosis]]; however, considered a separate entity.<ref>{{cite journal \|author=Otto CM \|title=Calcific aortic stenosis--time to look more closely at the valve \|journal=N. Engl. J. Med. \|volume=359 \|issue=13 \|pages=1395-8 \|year=2008 \|month=September \|pmid=18815402 \|doi=10.1056/NEJMe0807001 \|url=}}</ref>
			*Mitral valve is usually normal.
			*Most common cause of aortic stenosis.

			DDx of aortic stenosis:
			#Calcific aortic stenosis.
			#[[Bicuspid aortic valve]] with calcific aortic stenosis.
			#[[Rheumatic heart disease]].

			Clinical (mnemonic ''SAD''):
			*Syncope.
			*Angina.
			*Dyspnea (shortness of breath) - first symptom.

			==Microscopic==
			Features:<ref name=Ref_PBoD590>{{Ref PBoD\|590}}</ref>
			*[[Dystrophic calcification]]<ref name=pmid12779138>{{Cite journal \| last1 = Novaro \| first1 = GM. \| last2 = Griffin \| first2 = BP. \| title = Calcific aortic stenosis: another face of atherosclerosis? \| journal = Cleve Clin J Med \| volume = 70 \| issue = 5 \| pages = 471-7 \| month = May \| year = 2003 \| doi = \| PMID = 12779138 \| URL = http://www.ccjm.org/cgi/pmidlookup?view=long&pmid=12779138 }}</ref> - affects the valsalva side of the valve.
			**It affects the fibrosa.
			*Primarily at the base of the valve, i.e. there is relative sparing the free edge.

			Note:
			*There should be no [[neutrophil]]s and no microorganisms.
			*An expanded spongiosa layer may be seen in the context of calcification.{{fact}}

			DDx:
			*[[Infective endocarditis]] - inflammatory cells (esp. neutrophils), microorganisms (e.g. cocci).
			*[[Bicuspid aortic valve]].
			*[[Rheumatic heart disease]].

			==Sign out==
			<pre>
			AORTIC VALVE, VALVE REPLACEMENT:
			- CALCIFIC AORTIC STENOSIS.
			</pre>

			===Micro===
			The sections show valve tissue with marked calcification of the fibrosa layer. No neutrophils are identified. No microorganisms are identified with routine stains.

			==See also==
			*[[Heart valves]].
			*[[Atherosclerosis]].

			==References==
			{{Reflist\|2}}
	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: +cat.

2011-10-22T20:21:57Z

+cat.

← Older revision		Revision as of 20:21, 22 October 2011
Line 1:		Line 1:
	#redirect [[Heart_valves#Calcific_aortic_stenosis]]		#redirect [[Heart_valves#Calcific_aortic_stenosis]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-05-24T14:29:22Z

redirect for now

New page

#redirect [[Heart_valves#Calcific_aortic_stenosis]]

← Older revision		Revision as of 19:47, 15 November 2015
Line 102:		Line 102:
	*[[Heart valves]].		*[[Heart valves]].
	*[[Atherosclerosis]].		*[[Atherosclerosis]].
			*[[Congestive heart failure]].

	==References==		==References==