Dermatopathology - Revision history

Alessandro: two typos

2020-02-21T20:38:02Z

two typos

← Older revision		Revision as of 20:38, 21 February 2020
Line 46:		Line 46:
	*Melanocytes.		*Melanocytes.
	**Usuallly basal location.		**Usuallly basal location.
	**Epithelioid or ~~dentritic~~ morphology.		**Epithelioid or dendritic morphology.
	**Pericellular clearing - '''key feature'''.		**Pericellular clearing - '''key feature'''.
	**Clear cytoplasm.		**Clear cytoplasm.
Line 261:		Line 261:
	*[[Basal cell carcinoma]] (BCC).		*[[Basal cell carcinoma]] (BCC).
	*[[Malignant melanoma]].		*[[Malignant melanoma]].
	*~~Metstases~~.		*Metastases.

	==Non-malignant disease==		==Non-malignant disease==

Mitchell: /* Others */ Added a case

2017-05-09T20:41:50Z

Others: Added a case

← Older revision		Revision as of 20:41, 9 May 2017
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	</gallery>		</gallery>
	A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.		A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.

			===Herpes Zoster===
			<gallery>
			File:5.049889044 sl 1.png\| Changes of herpes zoster (A)
			File:5.049889044 sl 2.png\| Changes of herpes zoster (B)
			File:5.049889044 sl 3.png\| Changes of herpes zoster (C)
			File:5.049889044 sl 4.png\| Changes of herpes zoster (D)
			</gallery>
			Changes of herpes zoster in lower right abdominal skin of a 48 yo Hispanic man. A. Note the edema at the dermoepidermal junction along with a focal separation at the left as well as the inflamed superficial and deep blood vessels. B,C. Careful examination along the junction uncovers smudged chromatin diagnostic of viral infection. D. Vasculitis associated changes include extravasated neutrophils with nuclear dust, as well as pervascular macrophages, lymphocytes and occasional eosinophils.

	=References=		=References=

Jensflorian: /* Others */ layout fix

2017-04-27T11:46:22Z

Others: layout fix

← Older revision		Revision as of 11:46, 27 April 2017
Line 788:		Line 788:
	*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	<br>
	[[File:3767 dp sl 1.png \|Lipoid proteinosis]]		===Lipoid proteinosis===
	[[File:3767 dp sl 2.png \|Lipoid proteinosis]]<br>		<gallery>
	~~Lipoid proteinosis.~~ A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.		File:3767 dp sl 1.png \|Lipoid proteinosis (A)
	<br>		File:3767 dp sl 2.png \|Lipoid proteinosis (B)
	[[File:DP16MR17 sl 1.png\| Xanthogranuloma in scrotal skin.]]		</gallery>
	[[File:DP16MR17 sl 2.png\| Xanthogranuloma in scrotal skin.]]		A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.
	[[File:DP16MR17 sl 3.png\| Xanthogranuloma in scrotal skin.]]
	[[File:DP16MR17 sl 4.png\| Xanthogranuloma in scrotal skin.]]		===Xanthogranuloma in scrotal skin.===
	<br>		<gallery>
	~~Xanthogranuloma in scrotal skin.~~ A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.		File:DP16MR17 sl 1.png\| Xanthogranuloma in scrotal skin. (A)
	<br>		File:DP16MR17 sl 2.png\| Xanthogranuloma in scrotal skin. (B)
	[[File:DP13AP17 sl1.png\| Silicone granuloma]]		File:DP16MR17 sl 3.png\| Xanthogranuloma in scrotal skin. (C)
	[[File:DP13AP17 sl2.png\| Silicone granuloma]]		File:DP16MR17 sl 4.png\| Xanthogranuloma in scrotal skin. (D)
	[[File:DP13AP17 sl3.png\| Silicone granuloma]]		</gallery>
	[[File:DP13AP17 sl4.png\| Silicone granuloma]]		A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.
	<br>
	~~Silicone granuloma.~~ A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.		===Silicone granuloma===
	[[File:DP20AP17 sl 1.png\| Dermal histoplasmosis]]		<gallery>
	[[File:DP20AP17 sl 2.png\| Dermal histoplasmosis]]		File:DP13AP17 sl1.png\| Silicone granuloma (A)
	[[File:DP20AP17 sl 3.png\| Dermal histoplasmosis]]		File:DP13AP17 sl2.png\| Silicone granuloma (B)
	[[File:DP20AP17 sl 4.png\| Dermal histoplasmosis]]<br>		File:DP13AP17 sl3.png\| Silicone granuloma (C)
	~~Histoplasmosis in skin.~~ A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.		File:DP13AP17 sl4.png\| Silicone granuloma (D)
			</gallery>
			A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.

			====Histoplasmosis in skin====
			<gallery>
			File:DP20AP17 sl 1.png\| Dermal histoplasmosis (A)
			File:DP20AP17 sl 2.png\| Dermal histoplasmosis (B)
			File:DP20AP17 sl 3.png\| Dermal histoplasmosis (C)
			File:DP20AP17 sl 4.png\| Dermal histoplasmosis (D)
			</gallery>
			A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.

	=References=		=References=

Mitchell: /* Others */ added histoplasmosis

2017-04-20T14:38:07Z

Others: added histoplasmosis

← Older revision		Revision as of 14:38, 20 April 2017
Line 806:		Line 806:
	<br>		<br>
	Silicone granuloma. A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.		Silicone granuloma. A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.
			[[File:DP20AP17 sl 1.png\| Dermal histoplasmosis]]
			[[File:DP20AP17 sl 2.png\| Dermal histoplasmosis]]
			[[File:DP20AP17 sl 3.png\| Dermal histoplasmosis]]
			[[File:DP20AP17 sl 4.png\| Dermal histoplasmosis]]<br>
			Histoplasmosis in skin. A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.

	=References=		=References=

Mitchell: /* Others */

2017-04-13T14:23:38Z

Others

← Older revision		Revision as of 14:23, 13 April 2017
Line 800:		Line 800:
	Xanthogranuloma in scrotal skin. A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.		Xanthogranuloma in scrotal skin. A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.
	<br>		<br>
			[[File:DP13AP17 sl1.png\| Silicone granuloma]]
			[[File:DP13AP17 sl2.png\| Silicone granuloma]]
			[[File:DP13AP17 sl3.png\| Silicone granuloma]]
			[[File:DP13AP17 sl4.png\| Silicone granuloma]]
			<br>
			Silicone granuloma. A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.

	=References=		=References=

Mitchell: /* Others */ Added case

2017-03-16T19:21:55Z

Others: Added case

← Older revision		Revision as of 19:21, 16 March 2017
Line 788:		Line 788:
	*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
			<br>
	[[File:3767 dp sl 1.png \|Lipoid proteinosis]]		[[File:3767 dp sl 1.png \|Lipoid proteinosis]]
	[[File:3767 dp sl 2.png \|Lipoid proteinosis]]		[[File:3767 dp sl 2.png \|Lipoid proteinosis]]<br>
	Lipoid proteinosis. A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.		Lipoid proteinosis. A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.
			<br>
			[[File:DP16MR17 sl 1.png\| Xanthogranuloma in scrotal skin.]]
			[[File:DP16MR17 sl 2.png\| Xanthogranuloma in scrotal skin.]]
			[[File:DP16MR17 sl 3.png\| Xanthogranuloma in scrotal skin.]]
			[[File:DP16MR17 sl 4.png\| Xanthogranuloma in scrotal skin.]]
			<br>
			Xanthogranuloma in scrotal skin. A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.
			<br>

	=References=		=References=

Mitchell: /* Others */ added a case

2017-02-24T20:31:19Z

Others: added a case

← Older revision		Revision as of 20:31, 24 February 2017
Line 788:		Line 788:
	*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
			[[File:3767 dp sl 1.png \|Lipoid proteinosis]]
			[[File:3767 dp sl 2.png \|Lipoid proteinosis]]
			Lipoid proteinosis. A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.

	=References=		=References=

Michael: /* Layers of the epidermis */

2016-07-07T12:33:21Z

Layers of the epidermis

← Older revision		Revision as of 12:33, 7 July 2016
Line 29:		Line 29:
	===Epidermis===		===Epidermis===
	====Layers of the epidermis====		====Layers of the epidermis====
			[[Image:Epidermal layers.png\|thumb\|right\|Layers of the epidermis. (WC/Wbensmith)]]
	Epidermis layers - from the surface to epidermal-dermal junction:		Epidermis layers - from the surface to epidermal-dermal junction:
	*Stratum corneum.		*Stratum corneum.

Michael at 20:33, 5 May 2016

2016-05-05T20:33:56Z

← Older revision		Revision as of 20:33, 5 May 2016
Line 601:		Line 601:
	\| [[myxoid]] stroma		\| [[myxoid]] stroma
	\| raised, pearly, telangiectasia		\| raised, pearly, telangiectasia
	\| usu. none req., CK5/6+		\| usu. none req., [[CK5/6]]+
	\| [[trichoepithelioma]], [[basaloid squamous cell carcinoma]]		\| [[trichoepithelioma]], [[basaloid squamous cell carcinoma]]
	\| assoc. [[nevoid basal cell carcinoma syndrome]], [[Bazex syndrome]]		\| assoc. [[nevoid basal cell carcinoma syndrome]], [[Bazex syndrome]]

Michael: touch

2016-02-08T03:28:47Z

touch

← Older revision		Revision as of 03:28, 8 February 2016
Line 1:		Line 1:
	'''Dermatopathology''' is the pathology of skin.		'''Dermatopathology''' is the pathology of skin.

	Pathology is a significant part of dermatology and dermatologists spend five years in residency. So, it is a huge area.		Pathology is a significant part of dermatology and dermatologists spend five years in residency. So, it is a huge area.

← Older revision		Revision as of 11:46, 27 April 2017
Line 788:		Line 788:
	*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Dermatitis herpetiformis]]: gluten enteropathy ([[celiac disease]]), [[thyroid]] disease, intestinal [[lymphoma]].<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>		*[[Pemphigus vulgaris]]: [[thymoma]], myasthenia gravis, malignancy.<ref name=Ref_TN2007_D23>{{Ref TN2007\|D23}}</ref>
	<br>
	[[File:3767 dp sl 1.png \|Lipoid proteinosis]]		===Lipoid proteinosis===
	[[File:3767 dp sl 2.png \|Lipoid proteinosis]]<br>		<gallery>
	~~Lipoid proteinosis.~~ A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.		File:3767 dp sl 1.png \|Lipoid proteinosis (A)
	<br>		File:3767 dp sl 2.png \|Lipoid proteinosis (B)
	[[File:DP16MR17 sl 1.png\| Xanthogranuloma in scrotal skin.]]		</gallery>
	[[File:DP16MR17 sl 2.png\| Xanthogranuloma in scrotal skin.]]		A. Inner labial biopsy shows subepithelial hyalinized pink/red material, about blood vessels and in general. B. The particularly glassy appearance of the material in areas is evident at high power.
	[[File:DP16MR17 sl 3.png\| Xanthogranuloma in scrotal skin.]]
	[[File:DP16MR17 sl 4.png\| Xanthogranuloma in scrotal skin.]]		===Xanthogranuloma in scrotal skin.===
	<br>		<gallery>
	~~Xanthogranuloma in scrotal skin.~~ A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.		File:DP16MR17 sl 1.png\| Xanthogranuloma in scrotal skin. (A)
	<br>		File:DP16MR17 sl 2.png\| Xanthogranuloma in scrotal skin. (B)
	[[File:DP13AP17 sl1.png\| Silicone granuloma]]		File:DP16MR17 sl 3.png\| Xanthogranuloma in scrotal skin. (C)
	[[File:DP13AP17 sl2.png\| Silicone granuloma]]		File:DP16MR17 sl 4.png\| Xanthogranuloma in scrotal skin. (D)
	[[File:DP13AP17 sl3.png\| Silicone granuloma]]		</gallery>
	[[File:DP13AP17 sl4.png\| Silicone granuloma]]		A. Pseudoepitheliomatous hyperplasia seemingly forms a dermal mass. B. Parakeratosis tops epidermis. C. Neutrophils lie in the center of the apparent mass. D. Diagnostic xanthoma cells lie in dermal papillae.
	<br>
	~~Silicone granuloma.~~ A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.		===Silicone granuloma===
	[[File:DP20AP17 sl 1.png\| Dermal histoplasmosis]]		<gallery>
	[[File:DP20AP17 sl 2.png\| Dermal histoplasmosis]]		File:DP13AP17 sl1.png\| Silicone granuloma (A)
	[[File:DP20AP17 sl 3.png\| Dermal histoplasmosis]]		File:DP13AP17 sl2.png\| Silicone granuloma (B)
	[[File:DP20AP17 sl 4.png\| Dermal histoplasmosis]]<br>		File:DP13AP17 sl3.png\| Silicone granuloma (C)
	~~Histoplasmosis in skin.~~ A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.		File:DP13AP17 sl4.png\| Silicone granuloma (D)
			</gallery>
			A. The dermis resembles Swiss cheese. B. Macrophages, some with more than one nucleus, accompany empty ovoid spaces. C. Some macrophages resemble Teuton body giant cells. D. An admixture of lymphocytes is not at all unusual.

			====Histoplasmosis in skin====
			<gallery>
			File:DP20AP17 sl 1.png\| Dermal histoplasmosis (A)
			File:DP20AP17 sl 2.png\| Dermal histoplasmosis (B)
			File:DP20AP17 sl 3.png\| Dermal histoplasmosis (C)
			File:DP20AP17 sl 4.png\| Dermal histoplasmosis (D)
			</gallery>
			A. Extending from papillary dermis into dermis is a chronic, blue inflammatory infiltrate. B. The infiltrate comprises lymphocytes, plasma cells, and macrophages. C. At the edge of the biopsy pink strews inflammatory cells; this pink invasion of inflammation, so to speak, is a good place to look for organisms. D. High power reveals sometimes budding yeast forms in clear spaces.

	=References=		=References=