Gastric heterotopia of the duodenum - Revision history

Michael at 18:47, 5 February 2024

2024-02-05T18:47:57Z

← Older revision		Revision as of 18:47, 5 February 2024
Line 35:		Line 35:
	==General==		==General==
	*Common ~15% of cases in one series.<ref name=pmid22295146>{{Cite journal \| last1 = Terada \| first1 = T. \| title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. \| journal = Int J Clin Exp Pathol \| volume = 5 \| issue = 1 \| pages = 46-51 \| month = \| year = 2012 \| doi = \| PMID = 22295146 }}</ref>		*Common ~15% of cases in one series.<ref name=pmid22295146>{{Cite journal \| last1 = Terada \| first1 = T. \| title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. \| journal = Int J Clin Exp Pathol \| volume = 5 \| issue = 1 \| pages = 46-51 \| month = \| year = 2012 \| doi = \| PMID = 22295146 }}</ref>
	*Probably not ~~related to~~ [[Helicobacter pylori]].<ref name=pmid20656325>{{Cite journal \| last1 = Genta \| first1 = RM. \| last2 = Kinsey \| first2 = RS. \| last3 = Singhal \| first3 = A. \| last4 = Suterwala \| first4 = S. \| title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. \| journal = Hum Pathol \| volume = 41 \| issue = 11 \| pages = 1593-600 \| month = Nov \| year = 2010 \| doi = 10.1016/j.humpath.2010.04.010 \| PMID = 20656325 }}</ref>		*Probably ''not'' caused by ''[[Helicobacter pylori]]''.<ref name=pmid20656325>{{Cite journal \| last1 = Genta \| first1 = RM. \| last2 = Kinsey \| first2 = RS. \| last3 = Singhal \| first3 = A. \| last4 = Suterwala \| first4 = S. \| title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. \| journal = Hum Pathol \| volume = 41 \| issue = 11 \| pages = 1593-600 \| month = Nov \| year = 2010 \| doi = 10.1016/j.humpath.2010.04.010 \| PMID = 20656325 }}</ref>
			**''[[Helicobacter duodenitis]]'' is associated with gastric metaplasia.<ref name=pmid7769188>{{cite journal \|authors=Yang H, Dixon MF, Zuo J, Fong F, Zhou D, Corthésy I, Blum A \|title=Helicobacter pylori infection and gastric metaplasia in the duodenum in China \|journal=J Clin Gastroenterol \|volume=20 \|issue=2 \|pages=110–2 \|date=March 1995 \|pmid=7769188 \|doi=10.1097/00004836-199503000-00007 \|url=}}</ref>

	Clinical DDx:<ref name=pmid21242038/>		Clinical DDx:<ref name=pmid21242038/>

Michael at 13:10, 25 October 2022

2022-10-25T13:10:35Z

← Older revision		Revision as of 13:10, 25 October 2022
Line 72:		Line 72:

	==Sign out==		==Sign out==
			<pre>
			Duodenum, Biopsy:
			- Duodenal mucosa with gastric (body-type) heterotopia, otherwise within normal limits.
			</pre>

			===Block letters===
	<pre>		<pre>
	DUODENUM, BIOPSY:		DUODENUM, BIOPSY:
Line 78:		Line 84:
	</pre>		</pre>

	===Alternate===		====Alternate====
	<pre>		<pre>
	DUODENUM, BIOPSY:		DUODENUM, BIOPSY:

Michael: /* See also */

2017-01-26T16:49:00Z

Michael at 12:55, 3 May 2016

2016-05-03T12:55:11Z

← Older revision		Revision as of 12:55, 3 May 2016
Line 7:		Line 7:
	\| Micro = foveolar epithelium, gastric glands (body-type or antral-type), small bowel mucosa +/-Brunner's glands		\| Micro = foveolar epithelium, gastric glands (body-type or antral-type), small bowel mucosa +/-Brunner's glands
	\| Subtypes =		\| Subtypes =
	\| LMDDx = foveolar metaplasia ~~(isolated) - see [[chronic duodenitis]]~~, foveolar gastric-type dysplasia, [[intestinal metaplasia of the stomach]]		\| LMDDx = foveolar metaplasia of the duodenum, foveolar gastric-type dysplasia, [[intestinal metaplasia of the stomach]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
Line 58:		Line 58:

	DDx:		DDx:
	*Foveolar metaplasia (isolated) - see [[~~chronic~~ duodenitis]].		*Foveolar metaplasia (isolated) - see [[peptic duodenitis]].
	*Foveolar gastric-type dysplasia.<ref>{{Cite journal \| last1 = Park \| first1 = do Y. \| last2 = Srivastava \| first2 = A. \| last3 = Kim \| first3 = GH. \| last4 = Mino-Kenudson \| first4 = M. \| last5 = Deshpande \| first5 = V. \| last6 = Zukerberg \| first6 = LR. \| last7 = Song \| first7 = GA. \| last8 = Lauwers \| first8 = GY. \| title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 4 \| pages = 524-33 \| month = Apr \| year = 2008 \| doi = 10.1097/PAS.0b013e31815b890e \| PMID = 18300795 }}</ref>		*Foveolar gastric-type dysplasia.<ref>{{Cite journal \| last1 = Park \| first1 = do Y. \| last2 = Srivastava \| first2 = A. \| last3 = Kim \| first3 = GH. \| last4 = Mino-Kenudson \| first4 = M. \| last5 = Deshpande \| first5 = V. \| last6 = Zukerberg \| first6 = LR. \| last7 = Song \| first7 = GA. \| last8 = Lauwers \| first8 = GY. \| title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 4 \| pages = 524-33 \| month = Apr \| year = 2008 \| doi = 10.1097/PAS.0b013e31815b890e \| PMID = 18300795 }}</ref>
	*[[Stomach with intestinal metaplasia]].		*[[Stomach with intestinal metaplasia]].

Michael: /* See also */

2016-05-03T12:48:29Z

Michael: /* Microscopic */

2016-05-03T12:43:28Z

Microscopic

← Older revision		Revision as of 12:43, 3 May 2016
Line 55:		Line 55:
	#Foveolar epithelium.		#Foveolar epithelium.
	#Gastric glands - body-type or antral-type.		#Gastric glands - body-type or antral-type.
	*Small bowel mucosa +/- Brunner's glands.		#Small bowel mucosa +/- Brunner's glands.

	DDx:		DDx:

Michael at 12:43, 3 May 2016

2016-05-03T12:43:00Z

← Older revision		Revision as of 12:43, 3 May 2016
Line 1:		Line 1:
	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Gastric heterotopia in the duodenum -- high mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Gastric heterotopia in the duodenum. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = foveolar epithelium, gastric glands (body-type or antral-type), small bowel mucosa +/-Brunner's glands
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = foveolar metaplasia (isolated) - see [[chronic duodenitis]], foveolar gastric-type dysplasia, [[intestinal metaplasia of the stomach]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
Line 13:		Line 13:
	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = nodules/polyps
	\| Grossing =		\| Grossing =
	\| Staging =		\| Staging =
Line 55:		Line 55:
	#Foveolar epithelium.		#Foveolar epithelium.
	#Gastric glands - body-type or antral-type.		#Gastric glands - body-type or antral-type.
			*Small bowel mucosa +/- Brunner's glands.

	DDx:		DDx:
	*Foveolar metaplasia (isolated) - see [[chronic duodenitis]].		*Foveolar metaplasia (isolated) - see [[chronic duodenitis]].
	*Foveolar gastric-type dysplasia.<ref>{{Cite journal \| last1 = Park \| first1 = do Y. \| last2 = Srivastava \| first2 = A. \| last3 = Kim \| first3 = GH. \| last4 = Mino-Kenudson \| first4 = M. \| last5 = Deshpande \| first5 = V. \| last6 = Zukerberg \| first6 = LR. \| last7 = Song \| first7 = GA. \| last8 = Lauwers \| first8 = GY. \| title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 4 \| pages = 524-33 \| month = Apr \| year = 2008 \| doi = 10.1097/PAS.0b013e31815b890e \| PMID = 18300795 }}</ref>		*Foveolar gastric-type dysplasia.<ref>{{Cite journal \| last1 = Park \| first1 = do Y. \| last2 = Srivastava \| first2 = A. \| last3 = Kim \| first3 = GH. \| last4 = Mino-Kenudson \| first4 = M. \| last5 = Deshpande \| first5 = V. \| last6 = Zukerberg \| first6 = LR. \| last7 = Song \| first7 = GA. \| last8 = Lauwers \| first8 = GY. \| title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 4 \| pages = 524-33 \| month = Apr \| year = 2008 \| doi = 10.1097/PAS.0b013e31815b890e \| PMID = 18300795 }}</ref>
			*[[Stomach with intestinal metaplasia]].

	===Images===		===Images===

Michael: /* Classification */

2016-05-03T12:34:56Z

Classification

← Older revision		Revision as of 12:34, 3 May 2016
Line 46:		Line 46:

	Note:		Note:
	*This article considers the former (foveolar epithelium with gastric pits) as gastric heterotopia. The later ''foveolar ~~metaplasia of the duodenum''~~ is dealt with in the context of [[peptic duodenitis]].		*This article considers the former (foveolar epithelium with gastric pits) as gastric heterotopia. The later (foveolar epithelium only) is dealt with in the context of [[peptic duodenitis]]. <!-- ''foveolar metaplasia of the duodenum'' -->

	==Gross==		==Gross==

Michael at 12:33, 3 May 2016

2016-05-03T12:33:59Z

← Older revision		Revision as of 12:33, 3 May 2016
Line 1:		Line 1:
			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[duodenum]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = relatively common ~15%
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = duodenal polyp, duodenal ulcer, tumour/submucosal tumour, [[duodenal carcinoma]], [[duodenitis]]
			\| Tx =
			}}
	'''Gastric heterotopia of the duodenum''' is a relatively common finding of the [[duodenum]].		'''Gastric heterotopia of the duodenum''' is a relatively common finding of the [[duodenum]].

Line 5:		Line 37:
	*Probably not related to [[Helicobacter pylori]].<ref name=pmid20656325>{{Cite journal \| last1 = Genta \| first1 = RM. \| last2 = Kinsey \| first2 = RS. \| last3 = Singhal \| first3 = A. \| last4 = Suterwala \| first4 = S. \| title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. \| journal = Hum Pathol \| volume = 41 \| issue = 11 \| pages = 1593-600 \| month = Nov \| year = 2010 \| doi = 10.1016/j.humpath.2010.04.010 \| PMID = 20656325 }}</ref>		*Probably not related to [[Helicobacter pylori]].<ref name=pmid20656325>{{Cite journal \| last1 = Genta \| first1 = RM. \| last2 = Kinsey \| first2 = RS. \| last3 = Singhal \| first3 = A. \| last4 = Suterwala \| first4 = S. \| title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. \| journal = Hum Pathol \| volume = 41 \| issue = 11 \| pages = 1593-600 \| month = Nov \| year = 2010 \| doi = 10.1016/j.humpath.2010.04.010 \| PMID = 20656325 }}</ref>

	~~Can~~ be subdivided into:<ref name=pmid21242038>{{Cite journal \| last1 = Terada \| first1 = T. \| title = Heterotopic gastric mucosa of the gastrointestinal tract: a histopathologic study of 158 cases. \| journal = Pathol Res Pract \| volume = 207 \| issue = 3 \| pages = 148-50 \| month = Mar \| year = 2011 \| doi = 10.1016/j.prp.2010.12.004 \| PMID = 21242038 }}</ref>		Clinical DDx:<ref name=pmid21242038/>
			*Duodenal polyp, duodenal ulcer, tumour/submucosal tumour, [[duodenal carcinoma]], and [[duodenitis]].

			===Classification===
			According to Terada it can be subdivided into:<ref name=pmid21242038>{{Cite journal \| last1 = Terada \| first1 = T. \| title = Heterotopic gastric mucosa of the gastrointestinal tract: a histopathologic study of 158 cases. \| journal = Pathol Res Pract \| volume = 207 \| issue = 3 \| pages = 148-50 \| month = Mar \| year = 2011 \| doi = 10.1016/j.prp.2010.12.004 \| PMID = 21242038 }}</ref>
	#Foveolar epithelium with gastric pits		#Foveolar epithelium with gastric pits
	#Foveolar epithelium only.		#Foveolar epithelium only.

	~~Clinical DDx~~:~~<ref name=pmid21242038/>~~		Note:
	*~~Duodenal polyp, duodenal ulcer, tumour/submucosal tumour, [[duodenal carcinoma]], and~~ [[duodenitis]].		*This article considers the former (foveolar epithelium with gastric pits) as gastric heterotopia. The later ''foveolar metaplasia of the duodenum'' is dealt with in the context of [[peptic duodenitis]].

	==Gross==		==Gross==

Michael: /* General */

2016-05-03T12:27:02Z

General

← Older revision		Revision as of 12:27, 3 May 2016
Line 8:		Line 8:
	#Foveolar epithelium with gastric pits		#Foveolar epithelium with gastric pits
	#Foveolar epithelium only.		#Foveolar epithelium only.

			Clinical DDx:<ref name=pmid21242038/>
			*Duodenal polyp, duodenal ulcer, tumour/submucosal tumour, [[duodenal carcinoma]], and [[duodenitis]].

	==Gross==		==Gross==

← Older revision		Revision as of 16:49, 26 January 2017
Line 89:		Line 89:
	*[[Stomach]].		*[[Stomach]].
	*[[Gastric heterotopia]].		*[[Gastric heterotopia]].
			*[[Pseudopyloric mucous glands]].

	==References==		==References==

← Older revision		Revision as of 12:48, 3 May 2016
Line 88:		Line 88:
	*[[Duodenum]].		*[[Duodenum]].
	*[[Stomach]].		*[[Stomach]].
			*[[Gastric heterotopia]].

	==References==		==References==