Goblet cell adenocarcinoma - Revision history

Michael: tweak

2023-04-27T17:53:09Z

tweak

← Older revision		Revision as of 17:53, 27 April 2023
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	==General==		==General==
	*Rare appendiceal tumour that typically has an aggressive course vis-a-vis ~~other~~ appendiceal ~~carcinoids~~.<ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref>		*Rare appendiceal tumour that typically has an aggressive course vis-à-vis [[appendiceal carcinoid]]s.<ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref>
	*Mixed (biphasic) tumour with endocrine and exocrine features.		*Mixed (biphasic) tumour with endocrine and exocrine features.
	*Usually presents as [[acute appendicitis]].<ref name=pmid15967038/>		*Usually presents as [[acute appendicitis]].<ref name=pmid15967038/>

Michael at 17:48, 27 April 2023

2023-04-27T17:48:58Z

← Older revision		Revision as of 17:48, 27 April 2023
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	\| Width =		\| Width =
	\| Caption = Goblet cell adenocarcinoma. [[H&E stain]].		\| Caption = Goblet cell adenocarcinoma. [[H&E stain]].
	\| Synonyms = goblet cell carcinoid (obsolete term)		\| Synonyms = goblet cell carcinoid (obsolete term), crypt cell carcinoma
	\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance		\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance
	\| Subtypes =		\| Subtypes =
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	'''Goblet cell adenocarcinoma''' is a rare malignant tumour that is typically seen in the [[vermiform appendix]].<ref>{{cite journal \|authors=Kiyosawa N, Koyama M, Miyagawa Y, Kitazawa M, Tokumaru S, Soejima Y \|title=Goblet cell adenocarcinoma of the appendix: A case report of three cases \|journal=Int J Surg Case Rep \|volume=106 \|issue= \|pages=108229 \|date=April 2023 \|pmid=37084554 \|doi=10.1016/j.ijscr.2023.108229 \|url=}}</ref>		'''Goblet cell adenocarcinoma''' is a rare malignant tumour that is typically seen in the [[vermiform appendix]].<ref>{{cite journal \|authors=Kiyosawa N, Koyama M, Miyagawa Y, Kitazawa M, Tokumaru S, Soejima Y \|title=Goblet cell adenocarcinoma of the appendix: A case report of three cases \|journal=Int J Surg Case Rep \|volume=106 \|issue= \|pages=108229 \|date=April 2023 \|pmid=37084554 \|doi=10.1016/j.ijscr.2023.108229 \|url=}}</ref>

	It has gone by a number of different names in the past: '''crypt cell carcinoma''', '''goblet cell carcinoid'''<ref>{{cite journal \|authors=Sigley K, Franklin M, Welch S \|title=Appendiceal Goblet Cell Adenocarcinoma Case Report and Review of the Literature \|journal=Cureus \|volume=13 \|issue=2 \|pages=e13511 \|date=February 2021 \|pmid=33786220 \|pmc=7992912 \|doi=10.7759/cureus.13511 \|url=}}</ref><ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>		It has gone by a number of different names in the past: '''crypt cell carcinoma''',<ref>{{cite journal \|authors=Limaiem F, Omrani S, Hajri M \|title=Goblet cell adenocarcinoma of the ascending colon: An underrecognized diagnostic pitfall \|journal=Clin Case Rep \|volume=11 \|issue=1 \|pages=e6822 \|date=January 2023 \|pmid=36654693 \|pmc=9834544 \|doi=10.1002/ccr3.6822 \|url=}}</ref> '''goblet cell carcinoid'''<ref>{{cite journal \|authors=Sigley K, Franklin M, Welch S \|title=Appendiceal Goblet Cell Adenocarcinoma Case Report and Review of the Literature \|journal=Cureus \|volume=13 \|issue=2 \|pages=e13511 \|date=February 2021 \|pmid=33786220 \|pmc=7992912 \|doi=10.7759/cureus.13511 \|url=}}</ref><ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>
	and '''[[neuroendocrine tumour]] with goblet cell differentiation'''.		and '''[[neuroendocrine tumour]] with goblet cell differentiation'''.

Michael at 17:46, 27 April 2023

2023-04-27T17:46:42Z

← Older revision		Revision as of 17:46, 27 April 2023
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	\| Width =		\| Width =
	\| Caption = Goblet cell adenocarcinoma. [[H&E stain]].		\| Caption = Goblet cell adenocarcinoma. [[H&E stain]].
	\| Synonyms = ~~crypt~~ cell ~~carcinoma~~ (obsolete term)		\| Synonyms = goblet cell carcinoid (obsolete term)
	\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance		\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance
	\| Subtypes =		\| Subtypes =
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	'''Goblet cell adenocarcinoma''' is a rare malignant tumour that is typically seen in the [[vermiform appendix]].<ref>{{cite journal \|authors=Kiyosawa N, Koyama M, Miyagawa Y, Kitazawa M, Tokumaru S, Soejima Y \|title=Goblet cell adenocarcinoma of the appendix: A case report of three cases \|journal=Int J Surg Case Rep \|volume=106 \|issue= \|pages=108229 \|date=April 2023 \|pmid=37084554 \|doi=10.1016/j.ijscr.2023.108229 \|url=}}</ref>		'''Goblet cell adenocarcinoma''' is a rare malignant tumour that is typically seen in the [[vermiform appendix]].<ref>{{cite journal \|authors=Kiyosawa N, Koyama M, Miyagawa Y, Kitazawa M, Tokumaru S, Soejima Y \|title=Goblet cell adenocarcinoma of the appendix: A case report of three cases \|journal=Int J Surg Case Rep \|volume=106 \|issue= \|pages=108229 \|date=April 2023 \|pmid=37084554 \|doi=10.1016/j.ijscr.2023.108229 \|url=}}</ref>

	It has gone by a number of different names in the past: '''crypt cell carcinoma''', '''goblet cell carcinoid'''<ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>		It has gone by a number of different names in the past: '''crypt cell carcinoma''', '''goblet cell carcinoid'''<ref>{{cite journal \|authors=Sigley K, Franklin M, Welch S \|title=Appendiceal Goblet Cell Adenocarcinoma Case Report and Review of the Literature \|journal=Cureus \|volume=13 \|issue=2 \|pages=e13511 \|date=February 2021 \|pmid=33786220 \|pmc=7992912 \|doi=10.7759/cureus.13511 \|url=}}</ref><ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>
	and '''[[neuroendocrine tumour]] with goblet cell differentiation'''.		and '''[[neuroendocrine tumour]] with goblet cell differentiation'''.

Michael: tweak

2023-04-27T17:44:29Z

tweak

← Older revision		Revision as of 17:44, 27 April 2023
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	\| Image = Goblet_cell_carcinoid_-2-_very_high_mag.jpg		\| Image = Goblet_cell_carcinoid_-2-_very_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = ~~Crypt~~ cell ~~carcinoma~~. [[H&E stain]].		\| Caption = Goblet cell adenocarcinoma. [[H&E stain]].
			\| Synonyms = crypt cell carcinoma (obsolete term)
	\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance		\| Micro = small clusters of cells with stippled chromatin and a goblet cell-like appearance
	\| Subtypes =		\| Subtypes =

Michael: rename

2023-04-27T17:41:51Z

rename

← Older revision		Revision as of 17:41, 27 April 2023
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	\| ClinDDx = [[acute appendicitis]], other appendiceal tumours, other abdominal pathology		\| ClinDDx = [[acute appendicitis]], other appendiceal tumours, other abdominal pathology
	}}		}}
	'''~~Crypt~~ cell carcinoma''', ~~also known as~~ '''goblet cell carcinoid'''<ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>		'''Goblet cell adenocarcinoma''' is a rare malignant tumour that is typically seen in the [[vermiform appendix]].<ref>{{cite journal \|authors=Kiyosawa N, Koyama M, Miyagawa Y, Kitazawa M, Tokumaru S, Soejima Y \|title=Goblet cell adenocarcinoma of the appendix: A case report of three cases \|journal=Int J Surg Case Rep \|volume=106 \|issue= \|pages=108229 \|date=April 2023 \|pmid=37084554 \|doi=10.1016/j.ijscr.2023.108229 \|url=}}</ref>
	and '''[[neuroendocrine tumour]] with goblet cell differentiation'''~~, is a rare malignant tumour that is typically seen in the [[vermiform appendix]]~~.
			It has gone by a number of different names in the past: '''crypt cell carcinoma''', '''goblet cell carcinoid'''<ref name=pmid18042066>{{cite journal \|author=van Eeden S, Offerhaus GJ, Hart AA, ''et al.'' \|title=Goblet cell carcinoid of the appendix: a specific type of carcinoma \|journal=Histopathology \|volume=51 \|issue=6 \|pages=763–73 \|year=2007 \|month=December \|pmid=18042066 \|doi=10.1111/j.1365-2559.2007.02883.x \|url=}}</ref><ref name=pmid15967038>{{Cite journal \| last1 = Pahlavan \| first1 = PS. \| last2 = Kanthan \| first2 = R. \| title = Goblet cell carcinoid of the appendix. \| journal = World J Surg Oncol \| volume = 3 \| issue = \| pages = 36 \| month = Jun \| year = 2005 \| doi = 10.1186/1477-7819-3-36 \| PMID = 15967038 }}</ref>
			and '''[[neuroendocrine tumour]] with goblet cell differentiation'''.

	==General==		==General==

Michael: Michael moved page Crypt cell carcinoma to Goblet cell adenocarcinoma: new name

2023-04-27T17:38:37Z

Michael moved page Crypt cell carcinoma to Goblet cell adenocarcinoma: new name

← Older revision	Revision as of 17:38, 27 April 2023
(No difference)

Michael: /* Gross */

2017-03-05T22:00:06Z

Gross

← Older revision		Revision as of 22:00, 5 March 2017
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	==Gross==		==Gross==
	*Typically no mass is apparent at gross.<ref name=pmid15967038/>		*Typically no mass is apparent at gross.<ref name=pmid15967038/>

			Note:
			*Should be [[submitted in total]].

	==Microscopic==		==Microscopic==

Michael: /* Images */

2017-03-05T21:58:51Z

Images

← Older revision		Revision as of 21:58, 5 March 2017
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	===Images===		===Images===
			====Case 1====
	<gallery>		<gallery>
	Image:Goblet cell carcinoid - low mag.jpg\| CCC - low mag. (WC/Nephron)		Image:Goblet cell carcinoid - low mag.jpg\| CCC - low mag. (WC/Nephron)
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	Image:Goblet cell carcinoid -2- high mag.jpg\| CCC - high mag. (WC/Nephron)		Image:Goblet cell carcinoid -2- high mag.jpg\| CCC - high mag. (WC/Nephron)
	Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)		Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)
			</gallery>
			====Case 2====
			<gallery>
	Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)		Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)
	Image:Appendix Carcinoid GobletCell HP (5) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)		Image:Appendix Carcinoid GobletCell HP (5) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)

Michael at 05:34, 23 January 2017

2017-01-23T05:34:19Z

← Older revision		Revision as of 05:34, 23 January 2017
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid15967038>{{cite journal \|author=Pahlavan PS, Kanthan R \|title=Goblet cell carcinoid of the appendix \|journal=World J Surg Oncol \|volume=3 \|issue= \|pages=36 \|year=2005 \|month=June \|pmid=15967038 \|pmc=1182398 \|doi=10.1186/~~1477-7819-3-36 \|url=http://wjso.com/content/3/1/36}}</ref~~>		Features:<ref name=pmid15967038/>
	*Mixed neuroendocrine-nonneuroendocrine tumour;<ref name=pmid17684764>{{cite journal \|author=Volante M, Righi L, Asioli S, Bussolati G, Papotti M \|title=Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms \|journal=Virchows Arch. \|volume=451 Suppl 1 \|issue= \|pages=S61–9 \|year=2007 \|month=August \|pmid=17684764 \|doi=10.1007/s00428-007-0447-y \|url=}}</ref> features of both ''carcinoid'' and ''adenocarcinoma.<ref name=pmid15967038/>		*Mixed neuroendocrine-nonneuroendocrine tumour;<ref name=pmid17684764>{{cite journal \|author=Volante M, Righi L, Asioli S, Bussolati G, Papotti M \|title=Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms \|journal=Virchows Arch. \|volume=451 Suppl 1 \|issue= \|pages=S61–9 \|year=2007 \|month=August \|pmid=17684764 \|doi=10.1007/s00428-007-0447-y \|url=}}</ref> features of both ''carcinoid'' and ''adenocarcinoma.<ref name=pmid15967038/>
	**Archictecture: cells arranged in nests or clusters without a lumen.		**Archictecture: cells arranged in nests or clusters without a lumen.
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	**Synaptophysin +ve.		**Synaptophysin +ve.
	**Chromogranin +ve.		**Chromogranin +ve.
	*S-100 +ve.		*[[S-100]] +ve.
	*NSE +ve.		*NSE +ve.
	*Serotonin +ve.		*Serotonin +ve.

	Keratins:		Keratins:
	*Usually CK20 +ve > CK7 +ve.		*Usually [[CK20]] +ve > [[CK7]] +ve.

	*CEA +ve (membrane).		*CEA +ve (membrane).

	Notes:		Notes:
	*~~Nice review~~ of stains in Pahlavan and Kanthan.<ref name=pmid15967038>{{cite journal \|author=Pahlavan PS, Kanthan R \|title=Goblet cell carcinoid of the appendix \|journal=World J Surg Oncol \|volume=3 \|issue= \|pages=36 \|year=2005 \|month=June \|pmid=15967038 \|pmc=1182398 \|doi=10.1186/1477-7819-3-36 \|url=http:/~~/wjso.com/content/3/1/36}}</ref~~>		*Review of stains in Pahlavan and Kanthan.<ref name=pmid15967038/>

	==See also==		==See also==

Sarah: /* Images */

2015-03-11T10:15:56Z

Images

← Older revision		Revision as of 10:15, 11 March 2015
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	Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)		Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)
	Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)		Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP (5) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell MP PA.JPG\|Appendix - Goblet cell carcinoid - medium power (SKB)
			Image:Appendix Carcinoid GobletCell HP (4) - Copy PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP (3) - Copy PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP-2 PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP-2 (2) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
	</gallery>		</gallery>

← Older revision		Revision as of 10:15, 11 March 2015
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	Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)		Image:Goblet cell carcinoid -2- very high mag.jpg\| CCC - very high mag. (WC/Nephron)
	Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)		Image:Appendix Carcinoid GobletCell HP PA.JPG\|Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP (5) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell MP PA.JPG\|Appendix - Goblet cell carcinoid - medium power (SKB)
			Image:Appendix Carcinoid GobletCell HP (4) - Copy PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP (3) - Copy PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP-2 PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
			Image:Appendix Carcinoid GobletCell HP-2 (2) PA.JPG\|Appendix - Goblet cell carcinoid - high power (SKB)
	</gallery>		</gallery>