Hepatic adenoma - Revision history

Michael at 21:54, 29 September 2015

2015-09-29T21:54:30Z

2014-08-23T03:43:51Z

Microscopic

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	Features:		Features:
	*Sheets or cords of cells with mild variation of cell and nuclear size.<ref name=Ref_PBoD923>{{Ref PBoD\|923}}</ref>		*Sheets or cords of cells with mild variation of cell and nuclear size.<ref name=Ref_PBoD923>{{Ref PBoD\|923}}</ref>
	*Cords of cells ~~upto~~ 3 cells thick.<ref>STC S.19, 19 Jan 2009.</ref>		*Cords of cells up to 3 cells thick.<ref>STC S.19, 19 Jan 2009.</ref>
	*Cells may have cytoplasmic clearing due to glycogen or be pale - '''obvious if seen'''.		*Cells may have cytoplasmic clearing due to glycogen or be pale - '''obvious if seen'''.
	*Vascular - large arteries, dilated thin-walled veins.		*Vascular - large arteries, dilated thin-walled veins.

2014-08-23T03:42:30Z

← Older revision		Revision as of 03:42, 23 August 2014
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	\| Caption = Hepatic adenoma. [[H&E stain]].		\| Caption = Hepatic adenoma. [[H&E stain]].
	\| Synonyms = hepatocellular adenoma		\| Synonyms = hepatocellular adenoma
	\| Micro =		\| Micro = sheets or cords of cells with mild variation of cell and nuclear size; cords of cells up to 3 cells thick, vascular (large arteries, dilated thin-walled veins), +/-cytoplasmic clearing/pale (due to glycogen); negatives: no bile ducts, no portal tracts, no [[cirrhosis]]
	\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma		\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma
	\| LMDDx = [[hepatocellular carcinoma]] (well-differentiated), [[focal nodular hyperplasia]]		\| LMDDx = [[hepatocellular carcinoma]] (well-differentiated), [[focal nodular hyperplasia]]

2014-08-23T03:40:14Z

Microscopic

← Older revision		Revision as of 03:40, 23 August 2014
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	*No bile ducts.		*No bile ducts.
	*No portal tracts.		*No portal tracts.
	*No cirrhosis! If cirrhosis is present it isn't a hepatic adenoma - '''important'''.		*No [[cirrhosis]]! If cirrhosis is present it isn't a hepatic adenoma - '''important'''.

	DDx:		DDx:

2014-08-23T03:37:32Z

← Older revision		Revision as of 03:37, 23 August 2014
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	\| Micro =		\| Micro =
	\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma		\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma
	\| LMDDx =		\| LMDDx = [[hepatocellular carcinoma]] (well-differentiated), [[focal nodular hyperplasia]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

2014-08-23T03:36:41Z

2014-08-23T03:36:25Z

← Older revision		Revision as of 03:36, 23 August 2014
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Hepatic_adenoma_high_mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Hepatic adenoma. [[H&E stain]].
	\| Synonyms =		\| Synonyms = hepatocellular adenoma
	\| Micro =		\| Micro =
	\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma		\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma

2014-08-23T03:35:53Z

Images

← Older revision		Revision as of 03:35, 23 August 2014
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	===Images===		===Images===
	<gallery>		<gallery>
	Image:~~Hepatic_adenoma_low_mag~~.jpg \| ~~Hepatic adenoma~~. (WC/Nephron)		Image:Hepatic adenoma low mag.jpg \| Low mag. (WC/Nephron)
	Image:Hepatic_adenoma_low_mag_reticulin.jpg \| ~~Hepatic adenoma~~ - reticulin. (WC/Nephron)		Image:Hepatic_adenoma_high_mag.jpg \| High mag. (WC/Nephron)
			Image:Hepatic_adenoma_low_mag_reticulin.jpg \| Low mag. - reticulin (WC/Nephron)
			Image:Hepatic_adenoma_high_mag_reticulin.jpg \| High mag. - reticulin (WC/Nephron)
	</gallery>		</gallery>
	www:		www:

2014-08-23T03:32:11Z

+infobox

← Older revision		Revision as of 03:32, 23 August 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro =
			\| Subtypes = inflammatory hepatic adenoma ([[AKA]] ''telangiectatic adenoma''), hepatocyte nuclear factor 1 alpha-mutated hepatic adenoma, beta-catenin-mutated hepatic adenoma, unclassified hepatic adenoma
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = well-circumscribed, typically subcapsular
			\| Grossing =
			\| Site = [[liver]] - see ''[[liver neoplasms]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = women +/-[[OCP]] use
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads = subcapsular, well-circumscribed
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Hepatic adenoma''', also known as '''hepatocellular adenoma''' (abbreviated '''HCA'''), is a benign [[liver neoplasms\|neoplasm of the liver]].		'''Hepatic adenoma''', also known as '''hepatocellular adenoma''' (abbreviated '''HCA'''), is a benign [[liver neoplasms\|neoplasm of the liver]].

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	Features:<ref>STC S.20, 19 Jan 2009.</ref>		Features:<ref>STC S.20, 19 Jan 2009.</ref>
	*Often subcapsular location.		*Often subcapsular location.
	*Well circumscribed, but not encapsulated.		*Well-circumscribed, but not encapsulated.

	==Microscopic==		==Microscopic==

2014-08-23T03:27:57Z

← Older revision		Revision as of 03:27, 23 August 2014
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	'''Hepatic adenoma''', also known as '''hepatocellular adenoma''' (abbreviated '''HCA'''), is a benign neoplasm of the liver.		'''Hepatic adenoma''', also known as '''hepatocellular adenoma''' (abbreviated '''HCA'''), is a benign [[liver neoplasms\|neoplasm of the liver]].

	==General==		==General==