Hereditary leiomyomatosis and renal cell cancer - Revision history

Michael: Redirected page to Hereditary leiomyomatosis and renal cell carcinoma syndrome

2016-03-16T03:21:10Z

Redirected page to Hereditary leiomyomatosis and renal cell carcinoma syndrome

← Older revision		Revision as of 03:21, 16 March 2016
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	#redirect[[hereditary leiomyomatosis and renal cell carcinoma]]		#redirect[[hereditary leiomyomatosis and renal cell carcinoma syndrome]]

Michael: redirect

2014-08-25T13:42:11Z

redirect

← Older revision		Revision as of 13:42, 25 August 2014
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	'''Hereditary leiomyomatosis and renal cell cancer''' (also '''hereditary leiomyomatosis and renal cell cancer''') is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM\|136850}}</ref>		#redirect[[hereditary leiomyomatosis and renal cell carcinoma]]

	~~It is characterized by:<ref name=Ref_WMSP290>{{Ref WMSP\|290}}</ref>~~
	* [[~~Papillary renal cell carcinoma]] type 2.~~
	* Benign [[leiomyoma]]s skin/[[uterine leiomyoma\|uterus]].
	* Uterine [[leiomyosarcoma]].

	~~==IHC==~~
	*2SC +ve -- cytoplasmic,<ref name=pmid24309325 >{{Cite journal \| last1 = Reyes \| first1 = C. \| last2 = Karamurzin \| first2 = Y. \| last3 = Frizzell \| first3 = N. \| last4 = Garg \| first4 = K. \| last5 = Nonaka \| first5 = D. \| last6 = Chen \| first6 = YB. \| last7 = Soslow \| first7 = RA. \| title = Uterine smooth muscle tumors with features suggesting fumarate hydratase aberration: detailed morphologic analysis and correlation with S-(2-succino)-cysteine immunohistochemistry. \| journal = Mod Pathol \| volume = 27 \| issue = 7 \| pages = 1020-7 \| month = Jul \| year = 2014 \| doi = 10.1038/modpathol.2013.215 \| PMID = 24309325 }}</ref> cytoplasmic and nuclear.<ref name=pmid24441663>{{Cite journal \| last1 = Chen \| first1 = YB. \| last2 = Brannon \| first2 = AR. \| last3 = Toubaji \| first3 = A. \| last4 = Dudas \| first4 = ME. \| last5 = Won \| first5 = HH. \| last6 = Al-Ahmadie \| first6 = HA. \| last7 = Fine \| first7 = SW. \| last8 = Gopalan \| first8 = A. \| last9 = Frizzell \| first9 = N. \| title = Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 5 \| pages = 627-37 \| month = May \| year = 2014 \| doi = 10.1097/PAS.0000000000000163 \| PMID = 24441663 }}</ref>

	~~==See also==~~
	*[[Hereditary renal cell carcinoma]].

	~~==References==~~
	~~{{Reflist\|1}}~~

	~~[[Category:Syndromes~~]]

Michael at 13:35, 25 August 2014

2014-08-25T13:35:23Z

← Older revision		Revision as of 13:35, 25 August 2014
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	'''Hereditary leiomyomatosis and renal cell cancer''' is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM\|136850}}</ref>		'''Hereditary leiomyomatosis and renal cell cancer''' (also '''hereditary leiomyomatosis and renal cell cancer''') is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM\|136850}}</ref>

	It is characterized by:<ref name=Ref_WMSP290>{{Ref WMSP\|290}}</ref>		It is characterized by:<ref name=Ref_WMSP290>{{Ref WMSP\|290}}</ref>
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	* Benign [[leiomyoma]]s skin/[[uterine leiomyoma\|uterus]].		* Benign [[leiomyoma]]s skin/[[uterine leiomyoma\|uterus]].
	* Uterine [[leiomyosarcoma]].		* Uterine [[leiomyosarcoma]].

			==IHC==
			*2SC +ve -- cytoplasmic,<ref name=pmid24309325 >{{Cite journal \| last1 = Reyes \| first1 = C. \| last2 = Karamurzin \| first2 = Y. \| last3 = Frizzell \| first3 = N. \| last4 = Garg \| first4 = K. \| last5 = Nonaka \| first5 = D. \| last6 = Chen \| first6 = YB. \| last7 = Soslow \| first7 = RA. \| title = Uterine smooth muscle tumors with features suggesting fumarate hydratase aberration: detailed morphologic analysis and correlation with S-(2-succino)-cysteine immunohistochemistry. \| journal = Mod Pathol \| volume = 27 \| issue = 7 \| pages = 1020-7 \| month = Jul \| year = 2014 \| doi = 10.1038/modpathol.2013.215 \| PMID = 24309325 }}</ref> cytoplasmic and nuclear.<ref name=pmid24441663>{{Cite journal \| last1 = Chen \| first1 = YB. \| last2 = Brannon \| first2 = AR. \| last3 = Toubaji \| first3 = A. \| last4 = Dudas \| first4 = ME. \| last5 = Won \| first5 = HH. \| last6 = Al-Ahmadie \| first6 = HA. \| last7 = Fine \| first7 = SW. \| last8 = Gopalan \| first8 = A. \| last9 = Frizzell \| first9 = N. \| title = Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cancer: recognition of the syndrome by pathologic features and the utility of detecting aberrant succination by immunohistochemistry. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 5 \| pages = 627-37 \| month = May \| year = 2014 \| doi = 10.1097/PAS.0000000000000163 \| PMID = 24441663 }}</ref>

	==See also==		==See also==

Michael at 06:28, 25 July 2014

2014-07-25T06:28:44Z

← Older revision		Revision as of 06:28, 25 July 2014
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	==References==		==References==
	{{Reflist\|2}}		{{Reflist\|1}}

	[[Category:Syndromes]]		[[Category:Syndromes]]

Michael at 06:26, 25 July 2014

2014-07-25T06:26:16Z

← Older revision		Revision as of 06:26, 25 July 2014
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	'''Hereditary leiomyomatosis and renal cell cancer''' is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM\|136850~~}}</ref>:<ref name=Ref_WMSP290>{{Ref WMSP\|290~~}}</ref>		'''Hereditary leiomyomatosis and renal cell cancer''' is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM\|136850}}</ref>

	It is characterized by:		It is characterized by:<ref name=Ref_WMSP290>{{Ref WMSP\|290}}</ref>
	* [[Papillary renal cell carcinoma]] type 2.		* [[Papillary renal cell carcinoma]] type 2.
	* Benign [[leiomyoma]]s skin/[[uterine leiomyoma\|uterus]].		* Benign [[leiomyoma]]s skin/[[uterine leiomyoma\|uterus]].

Michael: create

2014-07-25T06:22:59Z

create

New page

'''Hereditary leiomyomatosis and renal cell cancer''' is an uncommon syndrome caused by FH (fumarate hydratase) gene mutations.<ref name=omim136850>{{OMIM|136850}}</ref>:<ref name=Ref_WMSP290>{{Ref WMSP|290}}</ref>

It is characterized by:
* [[Papillary renal cell carcinoma]] type 2.
* Benign [[leiomyoma]]s skin/[[uterine leiomyoma|uterus]].
* Uterine [[leiomyosarcoma]].

==See also==
*[[Hereditary renal cell carcinoma]].

==References==
{{Reflist|2}}

[[Category:Syndromes]]