Ischemic colitis - Revision history

Engy: /* Ischemia versus infection on biopsy */

2019-08-14T11:29:47Z

Ischemia versus infection on biopsy

← Older revision		Revision as of 11:29, 14 August 2019
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	\| 36%		\| 36%
	\|-		\|-
	\| Lamina propria - ~~hyalizization~~		\| Lamina propria - hyalinization
	\| 67%		\| 67%
	\| 0%		\| 0%

Brigitte at 21:06, 8 April 2018

2018-04-08T21:06:56Z

← Older revision		Revision as of 21:06, 8 April 2018
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	www:		www:
	*[http://www.flickr.com/photos/euthman/3385570758/ Ischemic colitis (flickr.com/euthman)].		*[http://www.flickr.com/photos/euthman/3385570758/ Ischemic colitis (flickr.com/euthman)].
	*[http://esynopsis.uchc.edu/eAtlas/GI/1018b.htm Ischemic colitis (uchc.edu)].

	==Sign out==		==Sign out==

Michael: /* Ischemia versus infection on biopsy */

2017-10-06T17:16:02Z

Ischemia versus infection on biopsy

← Older revision		Revision as of 17:16, 6 October 2017
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	===Ischemia versus infection on biopsy===		===Ischemia versus infection on biopsy===
	Dignan and Greenson<ref name=pmid9199649>{{Cite journal \| last1 = Dignan \| first1 = CR. \| last2 = Greenson \| first2 = JK. \| title = Can ischemic colitis be differentiated from C difficile colitis in biopsy specimens? \| journal = Am J Surg Pathol \| volume = 21 \| issue = 6 \| pages = 706-10 \| month = Jun \| year = 1997 \| doi = \| PMID = 9199649 }}</ref> ~~have~~ tabular comparison between ischemia and (''C. difficile'') infection.		Dignan and Greenson<ref name=pmid9199649>{{Cite journal \| last1 = Dignan \| first1 = CR. \| last2 = Greenson \| first2 = JK. \| title = Can ischemic colitis be differentiated from C difficile colitis in biopsy specimens? \| journal = Am J Surg Pathol \| volume = 21 \| issue = 6 \| pages = 706-10 \| month = Jun \| year = 1997 \| doi = \| PMID = 9199649 }}</ref> created a tabular comparison between ischemia and (''C. difficile'') infection.

	A modified version of the Dignan-Greenson table (below) shows that the two etiologies generally cannot be separated; however, hyalinization appears to be useful if it is present:		A modified version of the Dignan-Greenson table (below) shows that the two etiologies generally cannot be separated; however, hyalinization appears to be useful if it is present:

Michael: /* Tabular comparison - ischemia versus infection */

2017-10-06T17:11:56Z

Tabular comparison - ischemia versus infection

← Older revision		Revision as of 17:11, 6 October 2017
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	*[[Infectious colitis]].		*[[Infectious colitis]].

	===~~Tabular comparison - ischemia~~ versus infection===		===Ischemia versus infection on biopsy===
	Dignan and Greenson<ref name=pmid9199649>{{Cite journal \| last1 = Dignan \| first1 = CR. \| last2 = Greenson \| first2 = JK. \| title = Can ischemic colitis be differentiated from C difficile colitis in biopsy specimens? \| journal = Am J Surg Pathol \| volume = 21 \| issue = 6 \| pages = 706-10 \| month = Jun \| year = 1997 \| doi = \| PMID = 9199649 }}</ref> have tabular comparison between ischemia and (''C. difficile'') infection. A modified version of the Dignan-Greenson table (below) shows that the two etiologies generally cannot be separated:		Dignan and Greenson<ref name=pmid9199649>{{Cite journal \| last1 = Dignan \| first1 = CR. \| last2 = Greenson \| first2 = JK. \| title = Can ischemic colitis be differentiated from C difficile colitis in biopsy specimens? \| journal = Am J Surg Pathol \| volume = 21 \| issue = 6 \| pages = 706-10 \| month = Jun \| year = 1997 \| doi = \| PMID = 9199649 }}</ref> have tabular comparison between ischemia and (''C. difficile'') infection.

			A modified version of the Dignan-Greenson table (below) shows that the two etiologies generally cannot be separated; however, hyalinization appears to be useful if it is present:
	{\| class="wikitable sortable"		{\| class="wikitable sortable"
	! Histologic feature		! Histologic feature
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	\| 28%		\| 28%
	\|}		\|}

	===Images===		===Images===
	<gallery>		<gallery>

Michael: /* Microscopic */ tabular comparison

2017-10-06T17:06:18Z

Microscopic: tabular comparison

← Older revision		Revision as of 17:06, 6 October 2017
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	*+/-Reactive epithelial changes - may mimic dysplasia.<ref name=pmid11175639/>		*+/-Reactive epithelial changes - may mimic dysplasia.<ref name=pmid11175639/>

	~~Note~~:		Notes:
	*Pseudomembranes arise from the crypts - considered ''acute''.		*Pseudomembranes arise from the crypts - considered ''acute''.

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	*[[Infectious colitis]].		*[[Infectious colitis]].

			===Tabular comparison - ischemia versus infection===
			Dignan and Greenson<ref name=pmid9199649>{{Cite journal \| last1 = Dignan \| first1 = CR. \| last2 = Greenson \| first2 = JK. \| title = Can ischemic colitis be differentiated from C difficile colitis in biopsy specimens? \| journal = Am J Surg Pathol \| volume = 21 \| issue = 6 \| pages = 706-10 \| month = Jun \| year = 1997 \| doi = \| PMID = 9199649 }}</ref> have tabular comparison between ischemia and (''C. difficile'') infection. A modified version of the Dignan-Greenson table (below) shows that the two etiologies generally cannot be separated:
			{\| class="wikitable sortable"
			! Histologic feature
			!Ischemia (24 cases)
			!Infection (25 cases)
			\|-
			\| Atrophic crypts
			\| 75%
			\| 24%
			\|-
			\| Lamina propria - haemorrhage
			\| 75%
			\| 36%
			\|-
			\| Lamina propria - hyalizization
			\| 67%
			\| 0%
			\|-
			\| Diffuse (histologic) pseudomembranes
			\| 25%
			\| 4%
			\|-
			\| Mucosal necrosis (full thickness)
			\| 58%
			\| 28%
			\|}
	===Images===		===Images===
	<gallery>		<gallery>

Michael: /* Biopsy */

2016-08-29T20:51:25Z

Biopsy

← Older revision		Revision as of 20:51, 29 August 2016
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	etiologies and, less likely, inflammatory bowel disease. Clinical		etiologies and, less likely, inflammatory bowel disease. Clinical
	correlation is required.		correlation is required.
			</pre>

			===Biopsy with nonspecific findings/compatible===
			<pre>
			Colon, Random Biopsies:
			- Mild acute colitis with mild eosinophilia, see comment.
			- NEGATIVE for significant architectural distortion.

			Comment:
			The colitis could be due to ischemia, drug reaction, infection or inflammatory
			bowel disease. Clinical correlation is required.
	</pre>		</pre>

Michael: /* See also */

2016-05-20T21:55:20Z

Michael: /* Sign out */

2016-05-07T19:46:18Z

Sign out

← Older revision		Revision as of 19:46, 7 May 2016
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	==Sign out==		==Sign out==
	===Biopsy===		===Biopsy===
			<pre>
			Left Colon, Biopsy:
			- Compatible with ischemic colitis (attenuated epithelium, hyalinized
			lamina propria, cryptitis).

			Comment:
			The differential diagnosis includes: drug reaction, infectious etiologies and, less likely, inflammatory bowel disease. Clinical correlation is required.
			</pre>

			====Block letters====
	<pre>		<pre>
	TRANSVERSE COLON, BIOPSY:		TRANSVERSE COLON, BIOPSY:

Michael: /* Microscopic */

2015-01-15T15:50:19Z

Microscopic

← Older revision		Revision as of 15:50, 15 January 2015
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	Features:		Features:
	*Withering crypts - '''important'''.		*Withering crypts - '''important'''.
	**Colonic epithelium has decreased cytoplasm - NC ratio increased.		**Colonic epithelium has decreased cytoplasm - [[NC ratio]] increased.
	**Usually with decreased goblet cells.		**Usually with decreased goblet cells.
	*Crypt loss/drop-out.		*Crypt loss/drop-out.

Michael: touch

2015-01-15T15:49:23Z

touch

← Older revision		Revision as of 15:49, 15 January 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Ischemic_colitis_-_high_mag.jpg		\| Image = Ischemic_colitis_-_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = Ischemic colitis. [[H&E stain]].		\| Caption = Ischemic colitis. [[H&E stain]].

← Older revision		Revision as of 21:55, 20 May 2016
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	*[[Colon]].		*[[Colon]].
	*[[Ischemic enteritis]].		*[[Ischemic enteritis]].
			*[[Colonic cast]].

	==References==		==References==