Nodal nevus - Revision history

Michael: tweak

2019-10-16T14:36:10Z

tweak

← Older revision		Revision as of 14:36, 16 October 2019
Line 29:		Line 29:
	\| Other =		\| Other =
	\| ClinDDx = [[lymph node metastasis]]		\| ClinDDx = [[lymph node metastasis]]
	\| Tx = none		\| Tx = none or follow-up
	}}		}}
	'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] finding that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>		'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] finding that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>
Line 37:		Line 37:
	==General==		==General==
	*[[Lymph node metastases]] from cutaneous melanoma are common and seen in approximately 20% of cases.<ref name=pmid28802493>{{Cite journal \| last1 = Prieto \| first1 = VG. \| title = Sentinel Lymph Nodes in Cutaneous Melanoma. \| journal = Clin Lab Med \| volume = 37 \| issue = 3 \| pages = 417-430 \| month = 09 \| year = 2017 \| doi = 10.1016/j.cll.2017.05.002 \| PMID = 28802493 }}</ref>		*[[Lymph node metastases]] from cutaneous melanoma are common and seen in approximately 20% of cases.<ref name=pmid28802493>{{Cite journal \| last1 = Prieto \| first1 = VG. \| title = Sentinel Lymph Nodes in Cutaneous Melanoma. \| journal = Clin Lab Med \| volume = 37 \| issue = 3 \| pages = 417-430 \| month = 09 \| year = 2017 \| doi = 10.1016/j.cll.2017.05.002 \| PMID = 28802493 }}</ref>
	*~~May~~ be confused with [[malignant melanoma]].<ref name=pmid27810606>{{Cite journal \| last1 = Davis \| first1 = J. \| last2 = Patil \| first2 = J. \| last3 = Aydin \| first3 = N. \| last4 = Mishra \| first4 = A. \| last5 = Misra \| first5 = S. \| title = Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma. \| journal = Int J Surg Case Rep \| volume = 29 \| issue = \| pages = 20-24 \| month = \| year = 2016 \| doi = 10.1016/j.ijscr.2016.10.040 \| PMID = 27810606 }}</ref>		*Nodal nevus may be confused with [[malignant melanoma]].<ref name=pmid27810606>{{Cite journal \| last1 = Davis \| first1 = J. \| last2 = Patil \| first2 = J. \| last3 = Aydin \| first3 = N. \| last4 = Mishra \| first4 = A. \| last5 = Misra \| first5 = S. \| title = Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma. \| journal = Int J Surg Case Rep \| volume = 29 \| issue = \| pages = 20-24 \| month = \| year = 2016 \| doi = 10.1016/j.ijscr.2016.10.040 \| PMID = 27810606 }}</ref>

	==Gross==		==Gross==

Michael at 03:54, 11 June 2019

2019-06-11T03:54:06Z

← Older revision		Revision as of 03:54, 11 June 2019
Line 31:		Line 31:
	\| Tx = none		\| Tx = none
	}}		}}
	'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] ~~findings~~ that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>		'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] finding that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>

	'''Nevus in lymph node''' and '''benign nevus cells in lymph node''' redirect here.		'''Nevus in lymph node''' and '''benign nevus cells in lymph node''' redirect here.

Michael: /* Microscopic */ +images

2019-06-11T03:53:47Z

Microscopic: +images

← Older revision		Revision as of 03:53, 11 June 2019
Line 53:		Line 53:
	DDx:		DDx:
	*[[Malignant melanoma]].		*[[Malignant melanoma]].

			===Images===
			<gallery>
			Image: Nodal nevus -- very low mag.jpg \| NN - very low mag. (WC)
			Image: Nodal nevus -- low mag.jpg \| NN - low mag. (WC)
			Image: Nodal nevus -- intermed mag.jpg \| NN - intermed. mag. (WC)
			Image: Nodal nevus -- high mag.jpg \| NN - high mag. (WC)
			Image: Nodal nevus -- very high mag.jpg \| NN - very high mag. (WC)
			</gallery>

	==IHC==		==IHC==

Michael at 03:51, 11 June 2019

2019-06-11T03:51:57Z

← Older revision		Revision as of 03:51, 11 June 2019
Line 33:		Line 33:
	'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>		'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>

	'''Nevus in lymph node''' and '''benign nevus cells in lymph node'' redirect here.		'''Nevus in lymph node''' and '''benign nevus cells in lymph node''' redirect here.

	==General==		==General==

Michael at 03:51, 11 June 2019

2019-06-11T03:51:48Z

← Older revision		Revision as of 03:51, 11 June 2019
Line 33:		Line 33:
	'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>		'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>

	''Nevus in lymph node'' ~~redirects~~ here.		'''Nevus in lymph node''' and '''benign nevus cells in lymph node'' redirect here.

	==General==		==General==

Michael at 03:51, 11 June 2019

2019-06-11T03:51:04Z

← Older revision		Revision as of 03:51, 11 June 2019
Line 1:		Line 1:
	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Nodal nevus -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption =
	\| Synonyms = capsular nevus, benign nevus cells in lymph node		\| Synonyms = capsular nevus, benign nevus cells in lymph node
	\| Micro =		\| Micro = bland nevus cells (lack prominent nucleoli, [[nuclear pleomorphism]], proliferative activity)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[malignant melanoma]]		\| LMDDx = [[malignant melanoma]]

Michael: +infobox

2019-06-11T03:49:21Z

+infobox

← Older revision		Revision as of 03:49, 11 June 2019
Line 1:		Line 1:
			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms = capsular nevus, benign nevus cells in lymph node
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[malignant melanoma]]
			\| Stains =
			\| IHC = S-100 +ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = usually not apparent
			\| Grossing =
			\| Staging =
			\| Site = [[lymph node]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = none
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = [[lymph node metastasis]]
			\| Tx = none
			}}
	'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>		'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal \| last1 = Lee \| first1 = JJ. \| last2 = Granter \| first2 = SR. \| last3 = Laga \| first3 = AC. \| last4 = Saavedra \| first4 = AP. \| last5 = Zhan \| first5 = Q. \| last6 = Guo \| first6 = W. \| last7 = Xu \| first7 = S. \| last8 = Murphy \| first8 = GF. \| last9 = Lian \| first9 = CG. \| title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. \| journal = Mod Pathol \| volume = 28 \| issue = 2 \| pages = 218-29 \| month = Feb \| year = 2015 \| doi = 10.1038/modpathol.2014.99 \| PMID = 25081754 }}</ref>

Michael: create

2019-06-11T03:20:58Z

create

New page

'''Nodal nevus''', also '''capsular nevus''', is benign [[lymph node]] findings that can be mistaken for [[malignant melanoma]].<ref name=pmid25081754>{{Cite journal | last1 = Lee | first1 = JJ. | last2 = Granter | first2 = SR. | last3 = Laga | first3 = AC. | last4 = Saavedra | first4 = AP. | last5 = Zhan | first5 = Q. | last6 = Guo | first6 = W. | last7 = Xu | first7 = S. | last8 = Murphy | first8 = GF. | last9 = Lian | first9 = CG. | title = 5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies. | journal = Mod Pathol | volume = 28 | issue = 2 | pages = 218-29 | month = Feb | year = 2015 | doi = 10.1038/modpathol.2014.99 | PMID = 25081754 }}</ref>

''Nevus in lymph node'' redirects here.

==General==
*[[Lymph node metastases]] from cutaneous melanoma are common and seen in approximately 20% of cases.<ref name=pmid28802493>{{Cite journal | last1 = Prieto | first1 = VG. | title = Sentinel Lymph Nodes in Cutaneous Melanoma. | journal = Clin Lab Med | volume = 37 | issue = 3 | pages = 417-430 | month = 09 | year = 2017 | doi = 10.1016/j.cll.2017.05.002 | PMID = 28802493 }}</ref>
*May be confused with [[malignant melanoma]].<ref name=pmid27810606>{{Cite journal | last1 = Davis | first1 = J. | last2 = Patil | first2 = J. | last3 = Aydin | first3 = N. | last4 = Mishra | first4 = A. | last5 = Misra | first5 = S. | title = Capsular nevus versus metastatic malignant melanoma - a diagnostic dilemma. | journal = Int J Surg Case Rep | volume = 29 | issue = | pages = 20-24 | month = | year = 2016 | doi = 10.1016/j.ijscr.2016.10.040 | PMID = 27810606 }}</ref>

==Gross==
*Usually not apparent.

==Microscopic==
Features:
*Nevus cells with bland cytomorphology.
**Lack size variation, nucleoli.
**Non-proliferative.

Note:
*No standardized criteria.<ref name=pmid27810606/>

DDx:
*[[Malignant melanoma]].

==IHC==
Features:<ref name=pmid27810606/>
*S-100 +ve.

==References==
{{Reflist|1}}

[[Category:Diagnosis]]
[[Category:Dermatopathology]]
[[Category:Lymph node pathology]]