Nucleus-to-cytoplasm ratio - Revision history

Jensflorian: /* High NC ratio in cancer */ pretreatmant as other cause

2016-05-19T06:23:02Z

High NC ratio in cancer: pretreatmant as other cause

← Older revision		Revision as of 06:23, 19 May 2016
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	The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the large ''[[small round cell tumour]]'' group.		The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the large ''[[small round cell tumour]]'' group.
	*Many other tumours - see ''[[A long differential diagnosis of small blue cell tumours]]''.		*Many other tumours - see ''[[A long differential diagnosis of small blue cell tumours]]''.
			*Preoperative treatment may increase NC ratio - example: pituitary adenoma under bromocriptine treatment.<ref>{{Cite journal \| last1 = Nissim \| first1 = M. \| last2 = Ambrosi \| first2 = B. \| last3 = Bernasconi \| first3 = V. \| last4 = Giannattasio \| first4 = G. \| last5 = Giovanelli \| first5 = MA. \| last6 = Bassetti \| first6 = M. \| last7 = Vaccari \| first7 = U. \| last8 = Moriondo \| first8 = P. \| last9 = Spada \| first9 = A. \| title = Bromocriptine treatment of macroprolactinomas: studies on the time course of tumor shrinkage and morphology. \| journal = J Endocrinol Invest \| volume = 5 \| issue = 6 \| pages = 409-15 \| month = \| year = \| doi = 10.1007/BF03350542 \| PMID = 7169515 }}</ref>

	===Atypical cells with a normal NC ratio===		===Atypical cells with a normal NC ratio===

Michael at 05:13, 18 May 2016

2016-05-18T05:13:01Z

← Older revision		Revision as of 05:13, 18 May 2016
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	High NC ratio is a strong predictor of [[malignancy]].<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}		High NC ratio is a strong predictor of [[malignancy]].<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}
	</ref> Like very rule, there are exceptions.		</ref> Like very rule, there are exceptions.

			NC ratio is a better predictor of malignancy than increased nuclear size.

	===High NC ratio in normal cells===		===High NC ratio in normal cells===

Michael: fix gr

2015-04-19T13:05:48Z

fix gr

← Older revision		Revision as of 13:05, 19 April 2015
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	'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.		'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.

	High NC ratio is strong predictor of [[malignancy]].<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}		High NC ratio is a strong predictor of [[malignancy]].<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}
	</ref> Like very rule, there are exceptions.		</ref> Like very rule, there are exceptions.

Michael at 05:46, 16 September 2014

2014-09-16T05:46:50Z

← Older revision		Revision as of 05:46, 16 September 2014
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			[[Image:Small_cell_lung_cancer_-_cytology.jpg\|thumb\|200px\|Cells with a high NC ratio ([[small cell carcinoma]]).]]
	'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.		'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.

Michael: /* See also */

2014-09-16T05:44:54Z

Michael at 12:29, 8 October 2013

2013-10-08T12:29:43Z

← Older revision		Revision as of 12:29, 8 October 2013
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	'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.		'''Nucleus-to-cytoplasm ratio''', also '''nuclear-cytoplasmic ratio''', is the relative size of the nucleus to the cytoplasm. It is commonly abbreviated '''NC ratio'''.

	High NC ratio is strong predictor of malignancy.<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}		High NC ratio is strong predictor of [[malignancy]].<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}
	</ref> Like very rule, there are exceptions.		</ref> Like very rule, there are exceptions.

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	===High NC ratio in cancer===		===High NC ratio in cancer===
	The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the ''[[small round cell tumour]]'' group.		The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the large ''[[small round cell tumour]]'' group.
	*Many other tumours.		*Many other tumours - see ''[[A long differential diagnosis of small blue cell tumours]]''.

	===Atypical cells with a normal NC ratio===		===Atypical cells with a normal NC ratio===
	*[[Radiation changes]].		*[[Radiation changes]] - [[clinical history]] is important!
			*Many tumours.

	==See also==		==See also==

Michael at 12:24, 8 October 2013

2013-10-08T12:24:50Z

← Older revision		Revision as of 12:24, 8 October 2013
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	The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the ''[[small round cell tumour]]'' group.		The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the ''[[small round cell tumour]]'' group.
	*Many other tumours.		*Many other tumours.

			===Atypical cells with a normal NC ratio===
			*[[Radiation changes]].

	==See also==		==See also==

Michael: /* See also */ +link

2011-12-27T23:39:06Z

Michael: /* See also */

2011-12-27T23:36:20Z

Michael: subdivide

2011-12-27T23:36:01Z

subdivide

← Older revision		Revision as of 23:36, 27 December 2011
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	High NC ratio is strong predictor of malignancy.<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}		High NC ratio is strong predictor of malignancy.<ref name=pmid16556320>{{Cite journal \| last1 = Mehrotra \| first1 = R. \| last2 = Gupta \| first2 = A. \| last3 = Singh \| first3 = M. \| last4 = Ibrahim \| first4 = R. \| title = Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions. \| journal = Mol Cancer \| volume = 5 \| issue = \| pages = 11 \| month = \| year = 2006 \| doi = 10.1186/1476-4598-5-11 \| PMID = 16556320 \| URL = http://www.biomedcentral.com/1476-4598/5/11 }}
	</ref> Like very rule, there are exceptions:		</ref> Like very rule, there are exceptions.

	High NC ratio in normal cells:		===High NC ratio in normal cells===
	*Lymphocytes.		*Lymphocytes.

	Low NC ratio in cancer:		===Low NC ratio in cancer===
	*[[Fibrolamellar hepatocellular carcinoma]].		*[[Fibrolamellar hepatocellular carcinoma]].
	*[[Acinic cell carcinoma]].		*[[Acinic cell carcinoma]].
			*Many others.

	The classic malignant high NC ratio cell is:		===High NC ratio in cancer===
	*[[~~Small~~ cell carcinoma]].		The classic malignant high NC ratio cell is [[small cell carcinoma]], which is in the ''[[small round cell tumour]]'' group.
			*Many other tumours.
	~~Other malignant high NC ratio tumours are~~ the [[small round cell tumour]]s.

	==See also==		==See also==

← Older revision		Revision as of 05:44, 16 September 2014
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	==See also==		==See also==
	*[[Nuclear pleomorphism]].		*[[Nuclear pleomorphism]].
			*[[Nuclear atypia]].
	*[[Basics]].		*[[Basics]].
	*[[Cytologic features and malignancy]].		*[[Cytologic features and malignancy]].

← Older revision		Revision as of 23:39, 27 December 2011
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	*[[Nuclear pleomorphism]].		*[[Nuclear pleomorphism]].
	*[[Basics]].		*[[Basics]].
			*[[Cytologic features and malignancy]].

	==References==		==References==