Phyllodes tumour - Revision history

Michael: /* IHC */

2026-09-01T20:54:10Z

IHC

← Older revision		Revision as of 20:54, 1 September 2026
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	*ER.		*ER.
	*PR.		*PR.
	Stromal cells:<ref>{{cite journal \|authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO \|title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast \|journal=Hum Pathol \|volume=34 \|issue=10 \|pages=1009–15 \|date=October 2003 \|pmid=14608534 \|doi=10.1053/s0046-8177(03)00414-3 \|url=}}</ref>		Stromal cells:<ref name=pmid14608534>{{cite journal \|authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO \|title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast \|journal=Hum Pathol \|volume=34 \|issue=10 \|pages=1009–15 \|date=October 2003 \|pmid=14608534 \|doi=10.1053/s0046-8177(03)00414-3 \|url=}}</ref>
	*CD34 +ve.		*CD34 +ve.
	*BCL2 +ve.		*BCL2 +ve.
	*CK -ve.		*CK -ve.
			*GATA-3 -ve.<ref name=pmid23375642>{{cite journal \|authors=Cimino-Mathews A, Subhawong AP, Illei PB, Sharma R, Halushka MK, Vang R, Fetting JH, Park BH, Argani P \|title=GATA3 expression in breast carcinoma: utility in triple-negative, sarcomatoid, and metastatic carcinomas \|journal=Hum Pathol \|volume=44 \|issue=7 \|pages=1341–9 \|date=July 2013 \|pmid=23375642 \|pmc=3991123 \|doi=10.1016/j.humpath.2012.11.003 \|url=}}</ref>

	==Sign out==		==Sign out==

Michael: /* IHC */

2026-09-01T20:50:36Z

IHC

← Older revision		Revision as of 20:50, 1 September 2026
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	Epithelial component:		Epithelial component:
	*CK7 +ve.		*CK7 +ve.
			*ER.
			*PR.
	Stromal cells:<ref>{{cite journal \|authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO \|title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast \|journal=Hum Pathol \|volume=34 \|issue=10 \|pages=1009–15 \|date=October 2003 \|pmid=14608534 \|doi=10.1053/s0046-8177(03)00414-3 \|url=}}</ref>		Stromal cells:<ref>{{cite journal \|authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO \|title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast \|journal=Hum Pathol \|volume=34 \|issue=10 \|pages=1009–15 \|date=October 2003 \|pmid=14608534 \|doi=10.1053/s0046-8177(03)00414-3 \|url=}}</ref>
	*CD34 +ve.		*CD34 +ve.

Michael: /* Sign out */

2026-09-01T20:50:16Z

Sign out

← Older revision		Revision as of 20:50, 1 September 2026
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	* † Stromal overgrowth = epithelial elements absent in one low power field (LPF), defined as x40;<ref name=pmid17932112>{{cite journal \|author=Taira N, Takabatake D, Aogi K, ''et al'' \|title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin \|journal=Jpn. J. Clin. Oncol. \|volume=37 \|issue=10 \|pages=730-6 \|year=2007 \|month=October \|pmid=17932112 \|doi=10.1093/jjco/hym099 \|url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> ''LPF'' is not adequately defined - see [[LPFitis]].		* † Stromal overgrowth = epithelial elements absent in one low power field (LPF), defined as x40;<ref name=pmid17932112>{{cite journal \|author=Taira N, Takabatake D, Aogi K, ''et al'' \|title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin \|journal=Jpn. J. Clin. Oncol. \|volume=37 \|issue=10 \|pages=730-6 \|year=2007 \|month=October \|pmid=17932112 \|doi=10.1093/jjco/hym099 \|url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> ''LPF'' is not adequately defined - see [[LPFitis]].
	* ‡ ''HPF'' is not adequately defined - see [[HPFitis]].		* ‡ ''HPF'' is not adequately defined - see [[HPFitis]].

			==IHC==
			Epithelial component:
			*CK7 +ve.
			Stromal cells:<ref>{{cite journal \|authors=Dunne B, Lee AH, Pinder SE, Bell JA, Ellis IO \|title=An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast \|journal=Hum Pathol \|volume=34 \|issue=10 \|pages=1009–15 \|date=October 2003 \|pmid=14608534 \|doi=10.1053/s0046-8177(03)00414-3 \|url=}}</ref>
			*CD34 +ve.
			*BCL2 +ve.
			*CK -ve.

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Michael: /* Sign out */ update

2021-10-21T19:59:16Z

Sign out: update

← Older revision		Revision as of 19:59, 21 October 2021
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	<pre>		<pre>
	Right Breast Mass, Excision:		Right Breast Mass, Excision:
	- ~~Phyllodes~~ tumour.		- Benign phyllodes tumour.
	- NEGATIVE for malignancy.		- NEGATIVE for malignancy.
	</pre>		</pre>

Michael: /* Micro */ fix typo

2021-10-15T17:49:02Z

Micro: fix typo

← Older revision		Revision as of 17:49, 15 October 2021
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	====Micro====		====Micro====
	The sections show a well-circumscribed mass with a ~~left~~-like architecture. There is no stromal overgrowth or atypia. Proliferative activity is not readily apparent.		The sections show a well-circumscribed mass with a leaf-like architecture. There is no stromal overgrowth or atypia. Proliferative activity is not readily apparent.

	==See also==		==See also==

Mark: /* Images */

2018-06-02T09:42:18Z

Images

← Older revision		Revision as of 09:42, 2 June 2018
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	Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)
	Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)
	Image:Malignant phyllodes tumour.jpg \|Malignant phyllodes tumour - low mag (WC)]]		Image:Malignant phyllodes tumour.jpg \|Malignant phyllodes tumour - low mag (WC)
			Image:Malignant phyllodes tumour high magnification.jpg \|Malignant phyllodes tumour - high mag (WC)
	</gallery>		</gallery>

Mark: /* Images */

2018-06-02T09:36:09Z

Images

← Older revision		Revision as of 09:36, 2 June 2018
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	Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)
	Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)
			Image:Malignant phyllodes tumour.jpg \|Malignant phyllodes tumour - low mag (WC)]]
	</gallery>		</gallery>

Michael at 14:28, 20 June 2016

2016-06-20T14:28:49Z

← Older revision		Revision as of 14:28, 20 June 2016
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	'''Phyllodes tumour''' is a tumour of the intralobular breast stroma. It may be benign or [[malignant]].		'''Phyllodes tumour''' is a tumour of the intralobular breast stroma. It may be benign or [[malignant]].

	It was previously called '''cystosarcoma phyllodes'''.		It was previously called '''cystosarcoma phyllodes'''. It is a type of [[fibroepithelial tumours of the breast\|fibroepithelial tumour]].

	==General==		==General==

Michael: /* See also */

2016-02-02T22:39:17Z

Michael at 04:55, 15 February 2014

2014-02-15T04:55:18Z

← Older revision		Revision as of 04:55, 15 February 2014
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	\| Caption = Phyllodes tumour. [[H&E stain]].		\| Caption = Phyllodes tumour. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = either (1) or (2): (1) large slit-like spaces, (2) cellular stroma - may be myxoid; +/-infiltrative border, +/-mitoses, +/-nuclear atypia, +/-"stromal overgrowth" ~ stroma fills microscopic field		\| Micro = either (1) or (2): (1) large slit-like spaces, (2) cellular stroma - may be myxoid; +/-infiltrative border, +/-mitoses, +/-nuclear atypia, +/-"stromal overgrowth" ~ stroma fills microscopic field (see ''microscopic'' section)
	\| Subtypes = benign, borderline, malignant		\| Subtypes = benign, borderline, malignant
	\| LMDDx = [[fibroadenoma]], [[metaplastic breast carcinoma]], primary breast sarcoma, other [[sarcoma]]s		\| LMDDx = [[fibroadenoma]], [[metaplastic breast carcinoma]], primary breast sarcoma, other [[sarcoma]]s

← Older revision		Revision as of 09:42, 2 June 2018
Line 77:		Line 77:
	Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_very_low_mag.jpg \| Phyllodes tumour - very low mag. (WC/Nephron)
	Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)		Image:Phyllodes_tumour_-_low_mag.jpg \| Phyllodes tumour - low mag. (WC/Nephron)
	Image:Malignant phyllodes tumour.jpg \|Malignant phyllodes tumour - low mag (WC)]]		Image:Malignant phyllodes tumour.jpg \|Malignant phyllodes tumour - low mag (WC)
			Image:Malignant phyllodes tumour high magnification.jpg \|Malignant phyllodes tumour - high mag (WC)
	</gallery>		</gallery>

@@ Line 127: / Line 127: @@
 * † Stromal overgrowth = epithelial elements absent in one low power field (LPF), defined as x40;<ref name=pmid17932112>{{cite journal |author=Taira N, Takabatake D, Aogi K, ''et al'' |title=Phyllodes tumor of the breast: stromal overgrowth and histological classification are useful prognosis-predictive factors for local recurrence in patients with a positive surgical margin |journal=Jpn. J. Clin. Oncol. |volume=37 |issue=10 |pages=730-6 |year=2007 |month=October |pmid=17932112 |doi=10.1093/jjco/hym099 |url=http://jjco.oxfordjournals.org/cgi/reprint/37/10/730}}</ref> ''LPF'' is not adequately defined - see [[LPFitis]].
 * ‡ ''HPF'' is not adequately defined - see [[HPFitis]].
 ==See also==