Radiation changes - Revision history

Michael at 21:36, 2 November 2016

2016-11-02T21:36:53Z

← Older revision		Revision as of 21:36, 2 November 2016
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	\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)		\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[pleomorphic tumours]] - esp. [[sarcoma]]s, poorly differentiated carcinomas, drug/toxin effect, well-differentiated tumours in the background of radiation changes		\| LMDDx = [[pleomorphic tumours]] - esp. [[sarcoma]]s, poorly differentiated carcinomas, drug/toxin effect, well-differentiated tumours in the background of radiation changes, "[[giant cell cystitis]]"
	\| Stains =		\| Stains =
	\| IHC = Ki-67 low, pankeratin -ve (usu.)		\| IHC = Ki-67 low, pankeratin -ve (usu.)

2016-11-02T20:57:43Z

Microscopic

← Older revision		Revision as of 20:57, 2 November 2016
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	*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated nuclear changes.		*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated nuclear changes.
	*Atypia associated with [[drug toxicity\|drugs]].		*Atypia associated with [[drug toxicity\|drugs]].
			*"[[Giant cell cystitis]]" - benign mesenchymal atypia with or without inflammation.

	===Images===		===Images===

2016-04-14T17:53:24Z

2016-04-14T16:33:18Z

touch

← Older revision		Revision as of 16:33, 14 April 2016
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	\| Image = Radiation changes -- high mag.jpg		\| Image = Radiation changes -- high mag.jpg
	\| Width =		\| Width =
	\| Caption = Radiation changes. [[H&E stain]].		\| Caption = Radiation changes. [[H&E stain]].
	\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)		\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)
	\| Subtypes =		\| Subtypes =

2016-04-14T16:21:02Z

touch

← Older revision		Revision as of 16:21, 14 April 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Radiation changes -- high mag.jpg		\| Image = Radiation changes -- high mag.jpg
	\| Width =		\| Width =
	\| Caption = Radiation changes. [[H&E stain]].		\| Caption = Radiation changes. [[H&E stain]].

2015-11-07T07:23:47Z

brain

← Older revision		Revision as of 07:23, 7 November 2015
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	</gallery>		</gallery>

	====~~brain~~====		====Brain====
	<gallery>		<gallery>
	File:Glioblastoma-radiation changes HE.jpg \| [[Glioblastoma]] with RC (WC/jensflorian)		File:Glioblastoma-radiation changes HE.jpg \| [[Glioblastoma]] with RC (WC/jensflorian)
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	File:Pathology Brain Radiation Necrosis 2.jpg \| Radiation necrosis and gliosis (WC/Tdvorak)		File:Pathology Brain Radiation Necrosis 2.jpg \| Radiation necrosis and gliosis (WC/Tdvorak)
	</gallery>		</gallery>


	==IHC==		==IHC==

2015-09-21T20:37:45Z

RC in glioma therapy

← Older revision		Revision as of 20:37, 21 September 2015
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	Image: Prostate with radiation changes -- high mag.jpg \| Prostate with RC - high mag.		Image: Prostate with radiation changes -- high mag.jpg \| Prostate with RC - high mag.
	</gallery>		</gallery>

			====brain====
			<gallery>
			File:Glioblastoma-radiation changes HE.jpg \| [[Glioblastoma]] with RC (WC/jensflorian)
			File:Pathology Brain Radiation Necrosis 1.jpg \| Radiation necrosis (WC/Tdvorak)
			File:Pathology Brain Radiation Necrosis 2.jpg \| Radiation necrosis and gliosis (WC/Tdvorak)
			</gallery>


	==IHC==		==IHC==

2015-07-31T20:43:24Z

tweak

← Older revision		Revision as of 20:43, 31 July 2015
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	\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)		\| Micro = cytoplasmic vacuolation (usually abundant), enlarged nuclei - but usu. normal [[NC ratio]], no nuclear membrane irregularies, chromatin "smudgy", +/-multinucleation, +/-fibrosis (chronic change), +/-edema (acute change)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[pleomorphic tumours]] - esp. [[sarcoma]]s, poorly differentiated carcinomas, drug/toxin effect		\| LMDDx = [[pleomorphic tumours]] - esp. [[sarcoma]]s, poorly differentiated carcinomas, drug/toxin effect, well-differentiated tumours in the background of radiation changes
	\| Stains =		\| Stains =
	\| IHC = Ki-67 low, pankeratin -ve (usu.)		\| IHC = Ki-67 low, pankeratin -ve (usu.)
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	*[[Pleomorphic tumours]].		*[[Pleomorphic tumours]].
	*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated nuclear changes.		*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated nuclear changes.
			*Atypia associated with [[drug toxicity\|drugs]].

	===Images===		===Images===

2015-07-31T20:41:30Z

Microscopic

← Older revision		Revision as of 20:41, 31 July 2015
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	DDx:		DDx:
	*[[Pleomorphic tumours]].		*[[Pleomorphic tumours]].
	*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated ~~atypia~~.		*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated nuclear changes.

	===Images===		===Images===

2015-07-31T20:40:43Z

Microscopic

← Older revision		Revision as of 20:40, 31 July 2015
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	DDx:		DDx:
	*[[Pleomorphic tumours]].		*[[Pleomorphic tumours]].
	*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]].		*Well-differentiated carcinoma, e.g. [[postradiation prostatic carcinoma]], may go unnoticed in the background of radiation-associated atypia.

	===Images===		===Images===

← Older revision		Revision as of 17:53, 14 April 2016
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	==See also==		==See also==
	*[[Radiation colitis]].		*[[Radiation colitis]].
			*[[Radiation esophagitis]].
	*[[Radiation changes in cervical cytology]].		*[[Radiation changes in cervical cytology]].
	*[[Radiation changes of the endocervical epithelium]].		*[[Radiation changes of the endocervical epithelium]].