https://librepathology.org/w/index.php?action=history&feed=atom&title=Sinonasal_teratocarcinosarcoma 2026-05-28T07:56:22Z Revision history for this page on the wiki MediaWiki 1.36.3 https://librepathology.org/w/index.php?title=Sinonasal_teratocarcinosarcoma&diff=49950&oldid=prev 2019-03-23T14:00:43Z

<p>create</p> <p><b>New page</b></p><div>'''Sinonasal teratocarcinosarcoma''', abbreviated '''SNTCS''' is a rare malignant tumour of the [[head and neck pathology|neck and neck]].<br /> <br /> It is also known as '''teratoid carcinosarcoma''' and '''teratocarcinoma'''.&lt;ref&gt;{{Cite journal | last1 = Mohanty | first1 = S. | last2 = Somu | first2 = L. | last3 = Gopinath | first3 = M. | title = Sino nasal teratocarcinosarcoma-an interesting clinical entity. | journal = Indian J Surg | volume = 75 | issue = Suppl 1 | pages = 141-2 | month = Jun | year = 2013 | doi = 10.1007/s12262-012-0510-z | PMID = 24426542 }}&lt;/ref&gt; <br /> <br /> ''Sinonasal teratocarcinoma'' redirects here.<br /> <br /> ==General==<br /> *Estimated to be ~3% of head and neck malignancies.&lt;ref name=pmid28484539&gt;{{Cite journal | last1 = Kurmi | first1 = DJ. | last2 = Mittal | first2 = RS. | last3 = Sharma | first3 = A. | last4 = Gandhi | first4 = A. | last5 = Singhvi | first5 = S. | title = Sinonasal teratocarcinosarcoma involving nasal cavity, nasopharynx, and all paranasal sinuses with bilateral orbital and intracranial extension: A rare case report. | journal = Asian J Neurosurg | volume = 12 | issue = 2 | pages = 232-240 | month = | year = | doi = 10.4103/1793-5482.145559 | PMID = 28484539 }}&lt;/ref&gt;<br /> <br /> ==Gross==<br /> *Typically within nasal cavity/paranasal sinus.&lt;ref name=pmid28484539/&gt;<br /> *May be related to [[mixed germ cell tumour]] - as it may have the isochromosome p12.<br /> <br /> ==Microscopic==<br /> Features:<br /> *Malignant [[teratoma]] and [[carcinosarcoma]] - includes following components:<br /> **Epithelium.<br /> **Mesenchyme.<br /> **Primitive neuroectoderm.<br /> <br /> DDx:<br /> *[[Mixed germ cell tumour]].<br /> *[[Carcinosarcoma]].<br /> *[[Sarcomatoid squamous carcinoma]].<br /> <br /> ==Molecular==<br /> *May have isochromosome p12.&lt;ref&gt;{{Cite journal | last1 = Vranic | first1 = S. | last2 = Caughron | first2 = SK. | last3 = Djuricic | first3 = S. | last4 = Bilalovic | first4 = N. | last5 = Zaman | first5 = S. | last6 = Suljevic | first6 = I. | last7 = Lydiatt | first7 = WM. | last8 = Emanuel | first8 = J. | last9 = Gatalica | first9 = Z. | title = Hamartomas, teratomas and teratocarcinosarcomas of the head and neck: Report of 3 new cases with clinico-pathologic correlation, cytogenetic analysis, and review of the literature. | journal = BMC Ear Nose Throat Disord | volume = 8 | issue = | pages = 8 | month = Nov | year = 2008 | doi = 10.1186/1472-6815-8-8 | PMID = 19025657 }}&lt;/ref&gt;&lt;ref&gt;{{Cite journal | last1 = Thomas | first1 = J. | last2 = Adegboyega | first2 = P. | last3 = Iloabachie | first3 = K. | last4 = Mooring | first4 = JW. | last5 = Lian | first5 = T. | title = Sinonasal teratocarcinosarcoma with yolk sac elements: a neoplasm of somatic or germ cell origin? | journal = Ann Diagn Pathol | volume = 15 | issue = 2 | pages = 135-9 | month = Apr | year = 2011 | doi = 10.1016/j.anndiagpath.2010.01.004 | PMID = 20952296 }}&lt;/ref&gt;<br /> <br /> ==See also==<br /> *[[Head and neck pathology]].<br /> <br /> ==References==<br /> {{Reflist|1}}<br /> <br /> [[Category:Diagnosis]]<br /> [[Category:Head and neck pathology]]</div>

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