Thyroid-like follicular carcinoma of the kidney - Revision history

Michael at 21:20, 14 March 2016

2016-03-14T21:20:49Z

← Older revision		Revision as of 21:20, 14 March 2016
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	'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''' (abbreviated '''TLF-RCC'''), is a recently described rare [[kidney tumour]].		'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''' (abbreviated '''TLF-RCC''' or '''TLFRCC'''), is a recently described rare [[kidney tumour]].

	It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>		It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>

Michael: /* Microscopic */

2016-03-14T21:20:19Z

Microscopic

← Older revision		Revision as of 21:20, 14 March 2016
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid24025519/>		Features:<ref name=pmid24025519/>
	*Thyroid follicule-like structures - both ~~microfollicular~~ and/or microfollicular.		*Thyroid follicule-like structures - both macrofollicular and/or microfollicular.
	**Contain dense-appearing eosinophilic material.		**Contain dense-appearing eosinophilic material.
	*Encapuslated.		*Encapuslated.

Michael: /* Microscopic */

2014-12-11T18:22:29Z

Microscopic

← Older revision		Revision as of 18:22, 11 December 2014
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid24025519/>		Features:<ref name=pmid24025519/>
	Thyroid follicule-like structures - both microfollicular and/or microfollicular. *Contain dense-appearing eosinophilic material.		*Thyroid follicule-like structures - both microfollicular and/or microfollicular.
			**Contain dense-appearing eosinophilic material.
	*Encapuslated.		*Encapuslated.
	*Nuclei round and regular with prominent nucleoli ([[ISUP nucleolar grade]] 2 or 3).		*Nuclei round and regular with prominent nucleoli ([[ISUP nucleolar grade]] 2 or 3).

Michael: /* See also */

2014-10-27T06:01:13Z

Michael: /* Images */ more

2014-10-27T05:02:10Z

Images: more

← Older revision		Revision as of 05:02, 27 October 2014
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	===Images===		===Images===
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190304/figure/Fig3/ TLF-RCC (nih.gov)].<ref name=pmid25293503>{{Cite journal \| last1 = Ghaouti \| first1 = M. \| last2 = Roquet \| first2 = L. \| last3 = Baron \| first3 = M. \| last4 = Pfister \| first4 = C. \| last5 = Sabourin \| first5 = JC. \| title = Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature. \| journal = Diagn Pathol \| volume = 9 \| issue = 1 \| pages = 186 \| month = \| year = 2014 \| doi = 10.1186/s13000-014-0186-8 \| PMID = 25293503 }}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190304/figure/Fig3/ TLF-RCC (nih.gov)].<ref name=pmid25293503>{{Cite journal \| last1 = Ghaouti \| first1 = M. \| last2 = Roquet \| first2 = L. \| last3 = Baron \| first3 = M. \| last4 = Pfister \| first4 = C. \| last5 = Sabourin \| first5 = JC. \| title = Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature. \| journal = Diagn Pathol \| volume = 9 \| issue = 1 \| pages = 186 \| month = \| year = 2014 \| doi = 10.1186/s13000-014-0186-8 \| PMID = 25293503 }}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123569/figure/fig2/ TLF-RCC (nih.gov)].<ref name=pmid25133003>{{Cite journal \| last1 = Wu \| first1 = WW. \| last2 = Chu \| first2 = JT. \| last3 = Nael \| first3 = A. \| last4 = Rezk \| first4 = SA. \| last5 = Romansky \| first5 = SG. \| last6 = Shane \| first6 = L. \| title = Thyroid-like follicular carcinoma of the kidney in a young patient with history of pediatric acute lymphoblastic leukemia. \| journal = Case Rep Pathol \| volume = 2014 \| issue = \| pages = 313974 \| month = \| year = 2014 \| doi = 10.1155/2014/313974 \| PMID = 25133003 }}</ref>

	==IHC==		==IHC==

Michael at 05:00, 27 October 2014

2014-10-27T05:00:09Z

← Older revision		Revision as of 05:00, 27 October 2014
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	'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''', is a recently described rare [[kidney tumour]].		'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''' (abbreviated '''TLF-RCC'''), is a recently described rare [[kidney tumour]].

	It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>		It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>

Michael: /* Microscopic */

2014-10-27T04:59:39Z

Microscopic

← Older revision		Revision as of 04:59, 27 October 2014
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	**[[Follicular thyroid carcinoma]].		**[[Follicular thyroid carcinoma]].
	**[[Papillary thyroid carcinoma follicular variant]].		**[[Papillary thyroid carcinoma follicular variant]].

			===Images===
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190304/figure/Fig3/ TLF-RCC (nih.gov)].<ref name=pmid25293503>{{Cite journal \| last1 = Ghaouti \| first1 = M. \| last2 = Roquet \| first2 = L. \| last3 = Baron \| first3 = M. \| last4 = Pfister \| first4 = C. \| last5 = Sabourin \| first5 = JC. \| title = Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature. \| journal = Diagn Pathol \| volume = 9 \| issue = 1 \| pages = 186 \| month = \| year = 2014 \| doi = 10.1186/s13000-014-0186-8 \| PMID = 25293503 }}</ref>

	==IHC==		==IHC==

Michael at 04:57, 27 October 2014

2014-10-27T04:57:59Z

← Older revision		Revision as of 04:57, 27 October 2014
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	==References==		==References==
	{{Reflist\|2}}		{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:Kidney tumours]]		[[Category:Kidney tumours]]

Michael at 04:56, 27 October 2014

2014-10-27T04:56:13Z

← Older revision		Revision as of 04:56, 27 October 2014
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	'''Thyroid-like follicular carcinoma of the kidney''' is a recently described rare [[kidney tumour]].		'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''', is a recently described rare [[kidney tumour]].

	It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>		It is considered an emerging entity by the ''[[Vancouver classification\|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal \| last1 = Srigley \| first1 = JR. \| last2 = Delahunt \| first2 = B. \| last3 = Eble \| first3 = JN. \| last4 = Egevad \| first4 = L. \| last5 = Epstein \| first5 = JI. \| last6 = Grignon \| first6 = D. \| last7 = Hes \| first7 = O. \| last8 = Moch \| first8 = H. \| last9 = Montironi \| first9 = R. \| title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. \| journal = Am J Surg Pathol \| volume = 37 \| issue = 10 \| pages = 1469-89 \| month = Oct \| year = 2013 \| doi = 10.1097/PAS.0b013e318299f2d1 \| PMID = 24025519 }}</ref>

Michael: more

2014-10-23T21:10:52Z

← Older revision		Revision as of 21:10, 23 October 2014
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	==General==		==General==
	*Extremely rare.		*Extremely rare - less than 15 cases reported in the literature.<ref name=pmid24025519/>
			*Large age range (29-83 years old).

			==Gross==
			*Solid, brown and well circumscribed.

	==Microscopic==		==Microscopic==
	Features:		Features:<ref name=pmid24025519/>
	*Thyroid follicule-like structures ~~with~~ eosinophilic material.		Thyroid follicule-like structures - both microfollicular and/or microfollicular. *Contain dense-appearing eosinophilic material.
			*Encapuslated.
			*Nuclei round and regular with prominent nucleoli ([[ISUP nucleolar grade]] 2 or 3).

			DDx:
			*Metastatic carcinoma.
			**[[Follicular thyroid carcinoma]].
			**[[Papillary thyroid carcinoma follicular variant]].

			==IHC==
			Features:<ref name=pmid24025519/>
			*TTF-1 -ve.
			*Thyroglobulin -ve.
			*CK7 +ve/-ve.
			*PAX8 +ve/-ve.

	==See also==		==See also==

← Older revision		Revision as of 06:01, 27 October 2014
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	==See also==		==See also==
	*[[Kidney tumours]].		*[[Kidney tumours]].
			*[[Thyroid gland]].

	==References==		==References==