Tissue loss - Revision history

Michael: /* Sign out */

2022-01-14T15:44:39Z

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← Older revision		Revision as of 15:44, 14 January 2022
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	</pre>		</pre>

			===No tissue at gross/microscopy===
	<pre>		<pre>
	Submitted as "Gastric Antrum", Biopsy:		Submitted as "Gastric Antrum", Biopsy:

Michael: /* Tissue loss */

2022-01-14T15:27:29Z

Tissue loss

← Older revision		Revision as of 15:27, 14 January 2022
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	found. The missing tissue appears to have been lost during processing or it consisted of		found. The missing tissue appears to have been lost during processing or it consisted of
	material that is soluble in the processing fluids and dissolved.		material that is soluble in the processing fluids and dissolved.
			</pre>

			<pre>
			Submitted as "Gastric Antrum", Biopsy:
			- No tissue is identified, see comment.

			Comment:
			No tissue is seen at microscopy. The tissue block was examined: no tissue appears to be in the tissue block. At gross no tissue was apparent (see gross description).

			A re-biopsy should be considered within the clinical context.
	</pre>		</pre>

Michael: /* No tissue at microscopy */

2015-11-25T18:00:21Z

No tissue at microscopy

← Older revision		Revision as of 18:00, 25 November 2015
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	Three levels were examined. A re-biopsy should be considered		Three levels were examined. A re-biopsy should be considered
	within the clinical context.		within the clinical context.
			</pre>

			<pre>
			Submitted as "Left Upper Lobe, Lung", Biopsy:
			- INSUFFICIENT TISSUE FOR ASSESSMENT, see comment.

			Comment:
			No tissue is seen at microscopy. Two levels were examined.

			A re-biopsy should be considered within the clinical context.
	</pre>		</pre>

Michael: /* Sign out */

2014-08-29T19:04:32Z

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← Older revision		Revision as of 19:04, 29 August 2014
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	found. The missing tissue appears to have been lost during processing or it consisted of		found. The missing tissue appears to have been lost during processing or it consisted of
	material that is soluble in the processing fluids and dissolved.		material that is soluble in the processing fluids and dissolved.
			</pre>

			===No tissue at microscopy===
			<pre>
			"Bladder tumor", biopsy:
			- No tissue is identified at microscopy (see comment)

			Comment:
			Three levels were examined. A re-biopsy should be considered
			within the clinical context.
	</pre>		</pre>

Michael at 21:37, 10 April 2013

2013-04-10T21:37:06Z

← Older revision		Revision as of 21:37, 10 April 2013
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	In pathology, '''tissue loss''' is when less tissue ~~is identified at microscopy than at~~ the ~~time of~~ [[gross pathology\|gross]]. It is relatively common in small biopsies.		In pathology, '''tissue loss''' is when a section at microscopy appears to represent less tissue then one could reasonably expect from the [[gross pathology\|gross]]. It is relatively common in small biopsies.

	It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>		It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>

Michael at 21:30, 10 April 2013

2013-04-10T21:30:07Z

← Older revision		Revision as of 21:30, 10 April 2013
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	In pathology, '''tissue loss''' is when less tissue is identified at microscopy than at the time of gross. It is relatively common in small biopsies.		In pathology, '''tissue loss''' is when less tissue is identified at microscopy than at the time of [[gross pathology\|gross]]. It is relatively common in small biopsies.

	It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>		It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>

Michael at 19:45, 10 April 2013

2013-04-10T19:45:35Z

← Older revision		Revision as of 19:45, 10 April 2013
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	'''~~Tissue~~ loss''' is relatively common in small biopsies.		In pathology, '''tissue loss''' is when less tissue is identified at microscopy than at the time of gross. It is relatively common in small biopsies.

	It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>		It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>
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	*Pseudofragmentation - two piece of tissue appears to be two in the plane of section.		*Pseudofragmentation - two piece of tissue appears to be two in the plane of section.
	*[[Tissue floater]].		*[[Tissue floater]].

			===Work-up===
			:See ''[[tissue floater]]''.

	==Possible causes of tissue loss==		==Possible causes of tissue loss==
	*Tissue floated from the slide.		*Tissue floated from the slide.
	*Material submitted soluble in the processing medium, e.g. mucous.		*Material submitted is soluble in the processing medium, e.g. mucous.

	===Work-up===		===Work-up===

Michael: w

2013-04-10T19:41:50Z

← Older revision		Revision as of 19:41, 10 April 2013
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	'''Tissue loss''' is relatively common in small biopsies.		'''Tissue loss''' is relatively common in small biopsies.

	It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at gross and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>		It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at [[gross pathology\|gross]] and microscopy.<ref name=pmid22129184>{{Cite journal \| last1 = Owens \| first1 = SR. \| last2 = Wiehagen \| first2 = L. \| last3 = Simmons \| first3 = C. \| last4 = Sikorova \| first4 = A. \| last5 = Stewart \| first5 = W. \| last6 = Kelly \| first6 = S. \| last7 = Nestler \| first7 = R. \| last8 = Yousem \| first8 = SA. \| title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 12 \| pages = 1561-4 \| month = Dec \| year = 2011 \| doi = 10.5858/arpa.2011-0020-OA \| PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>

	This article also discusses '''tissue gain'''.		This article also discusses '''tissue gain'''.

Michael: /* Tissue loss */ fix

2013-04-10T19:39:31Z

Tissue loss: fix

← Older revision		Revision as of 19:39, 10 April 2013
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	<pre>		<pre>
	The block (A1) was melted to look for the missing core tissue; however, no tissue was		The block (A1) was melted to look for the missing core tissue; however, no tissue was
	found. The missing tissue appears to have been lost during processing or material that		found. The missing tissue appears to have been lost during processing or it consisted of
	is soluble in the processing fluids and dissolved. ~~The tissue~~		material that is soluble in the processing fluids and dissolved.
	</pre>		</pre>

Michael: create

2013-04-10T19:38:22Z

create

New page

'''Tissue loss''' is relatively common in small biopsies.

It is estimated that approximately 27% of cases have a mismatch between the number of pieces seen at gross and microscopy.<ref name=pmid22129184>{{Cite journal | last1 = Owens | first1 = SR. | last2 = Wiehagen | first2 = L. | last3 = Simmons | first3 = C. | last4 = Sikorova | first4 = A. | last5 = Stewart | first5 = W. | last6 = Kelly | first6 = S. | last7 = Nestler | first7 = R. | last8 = Yousem | first8 = SA. | title = Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory. | journal = Arch Pathol Lab Med | volume = 135 | issue = 12 | pages = 1561-4 | month = Dec | year = 2011 | doi = 10.5858/arpa.2011-0020-OA | PMID = 22129184 }}</ref> A tissue gain is seen in approximately 25% of cases and a tissue loss is seen in approximately 7% of cases.<ref name=pmid22129184/>

This article also discusses '''tissue gain'''.

==Possible cause of tissue gain==
*Tissue fragmentation.
*Pseudofragmentation - two piece of tissue appears to be two in the plane of section.
*[[Tissue floater]].

==Possible causes of tissue loss==
*Tissue floated from the slide.
*Material submitted soluble in the processing medium, e.g. mucous.

===Work-up===
*Melt the tissue block to looking for the lost tissue.

==Sign out==
===Tissue loss===
<pre>
The block (A1) was melted to look for the missing core tissue; however, no tissue was
found. The missing tissue appears to have been lost during processing or material that
is soluble in the processing fluids and dissolved. The tissue
</pre>

==See also==
*[[Tissue floater]].
*[[Quality]].

==References==
{{Reflist|1}}

[[Category:Quality]]