Splendore-Hoeppli phenomenon

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File:Actinomyces with Splendore-Hoeppli phenomenon.jpg
Suppurative lymphadenitis in the neck caused by Actinomyces infection. The eosinophilc rim represents the Splendore-Hoeppli phenomenon.

Deeply eosinophilic material, typically surrounding micro-organisms. It it thought to be composed of immunoglobulin and necrotic debris rich in microbial antigen.

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