Difference between revisions of "Neuroendocrine markers"
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'''Neuroendocrine markers''' are [[immunostains]] that suggest neuroendocrine differentiation. | '''Neuroendocrine markers''' are [[immunostains]] that suggest neuroendocrine differentiation. | ||
==Common markers== | |||
*Chromogranin A. | |||
**Considered the most specific neuroendocrine stain.<ref name=pmid20182342>{{Cite journal | last1 = McCluggage | first1 = WG. | last2 = Kennedy | first2 = K. | last3 = Busam | first3 = KJ. | title = An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63. | journal = Am J Surg Pathol | volume = 34 | issue = 4 | pages = 525-32 | month = Apr | year = 2010 | doi = 10.1097/PAS.0b013e3181d1d457 | PMID = 20182342 }}</ref> | |||
*Synaptophysin +ve. | |||
*[[CD56]]. | |||
**Less specific than chromogranin A and synaptophysin. | |||
==See also== | ==See also== | ||
Revision as of 17:42, 13 September 2014
Neuroendocrine markers are immunostains that suggest neuroendocrine differentiation.
Common markers
- Chromogranin A.
- Considered the most specific neuroendocrine stain.[1]
- Synaptophysin +ve.
- CD56.
- Less specific than chromogranin A and synaptophysin.
See also
- ↑ McCluggage, WG.; Kennedy, K.; Busam, KJ. (Apr 2010). "An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63.". Am J Surg Pathol 34 (4): 525-32. doi:10.1097/PAS.0b013e3181d1d457. PMID 20182342.