Difference between revisions of "Neuroendocrine markers"
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'''Neuroendocrine markers''' are [[immunostains]] that suggest neuroendocrine differentiation. | '''Neuroendocrine markers''' are [[immunostains]] that suggest neuroendocrine differentiation. | ||
==Common markers== | |||
*[[Chromogranin A]]. | |||
**Considered the most specific neuroendocrine stain.<ref name=pmid20182342>{{Cite journal | last1 = McCluggage | first1 = WG. | last2 = Kennedy | first2 = K. | last3 = Busam | first3 = KJ. | title = An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63. | journal = Am J Surg Pathol | volume = 34 | issue = 4 | pages = 525-32 | month = Apr | year = 2010 | doi = 10.1097/PAS.0b013e3181d1d457 | PMID = 20182342 }}</ref> | |||
*Synaptophysin +ve. | |||
*[[CD56]]. | |||
**Less specific than chromogranin A and synaptophysin. | |||
===Less common markers=== | |||
*NSE. | |||
*CD57. | |||
*[[PGP9.5]]. | |||
==See also== | ==See also== | ||
*[[Immunohistochemistry]]. | *[[Immunohistochemistry]]. | ||
*[[Neuroendocrine tumours]]. | *[[Neuroendocrine tumours]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category:Immunohistochemistry]] | [[Category:Immunohistochemistry]] | ||
Latest revision as of 18:15, 25 April 2018
Neuroendocrine markers are immunostains that suggest neuroendocrine differentiation.
Common markers
- Chromogranin A.
- Considered the most specific neuroendocrine stain.[1]
- Synaptophysin +ve.
- CD56.
- Less specific than chromogranin A and synaptophysin.
Less common markers
- NSE.
- CD57.
- PGP9.5.
See also
References
- ↑ McCluggage, WG.; Kennedy, K.; Busam, KJ. (Apr 2010). "An immunohistochemical study of cervical neuroendocrine carcinomas: Neoplasms that are commonly TTF1 positive and which may express CK20 and P63.". Am J Surg Pathol 34 (4): 525-32. doi:10.1097/PAS.0b013e3181d1d457. PMID 20182342.