Allograft biopsy categories (Banff 97):[1]
| Type
|
Key morphologic finding
|
| Normal
|
no inflammation
|
| Suspicious for acute rejection
|
focal mild tubulitis (1-4 mononuclear cells/tubular cross section)
|
| Acute/active rejection
|
tubulitis (>4 mononuclear cells/tubular cross section); see separate table for grading
|
| Chronic/sclerosing allograft nephropathy
|
interstitial fibrosis and tubular atrophy; see separate table for grading
|
| Type
|
Key morphologic finding
Acute/active rejection
Acute/active rejection in allograft biopsies (Banff 97):[1]
| Grade
|
Key morphologic finding
|
| IA
|
4< mononuclear cell/tubular cross section or 10 tubular cells <10; >25% of parenchyma
|
| IB
|
>10 mononuclear cell/tubular cross section or 10 tubular cells; >25% of parenchyma
|
| IIA
|
mild-to-moderate intimal arteritis; <=25% of luminal area
|
| IIB
|
severe intimal arteritis; >25% of luminal area
|
| III
|
transmural arteritis and/or fibrinoid necrosis
|
- ↑ 1.0 1.1 Fogo, Agnes B.; Kashgarian, Michael (2005). Diagnostic Atlas of Renal Pathology: A Companion to Brenner and Rector's The Kidney 7E (1st ed.). Saunders. pp. 400. ISBN 978-1416028710.
|